<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01984

Description Mediator of RNA polymerase II transcription subunit 23 (Fragment)
SequenceETQLESIFEEVVKTEVIEEAFPGMFMDTPEDERTKLISCLGAFRQFWSSLSQESHEQCVQWIVRFIHSQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVVAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAMCNSWKLDPTTLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAHSDNSKLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGNMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSLALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPAPLQVFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIIAHFSVQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMSYHKKYPEKLYFEGLAEQVNPPVQIQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERHLRERTNLKRKLVHAIIGSLKDNRPLGWCLSDTYLKCAMNAREDNPWIPDDAYYCKLIGRLVDNILRKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNELLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDCIVNVINSPSLTSETEWVGYPFQLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLIPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYEMLLNADRYSPHLNYMDPICDFLYHMKYMFTGDSVKDQVEKIICNLRPALKLRLRFITHISKMESAAAAQQPLSNGSPAPQPSQVPVNVALPVTQ
Length1353
PositionTail
OrganismTinamus guttatus (White-throated tinamou)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Palaeognathae> Tinamiformes> Tinamidae> Tinamus.
Aromaticity0.10
Grand average of hydropathy-0.022
Instability index45.78
Isoelectric point7.12
Molecular weight155128.58
Publications

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP01984
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.86|      14|      17|    1025|    1041|       1
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 1025- 1039 (24.65/22.32)	WCLSDTYLkCAMNAR
 1044- 1057 (29.22/13.76)	WIPDDAYY.CKLIGR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.20|      16|      19|     978|     993|       2
---------------------------------------------------------------------------
  978-  993 (31.52/20.48)	YKFHDRPVTYLYNTL.H
  995- 1011 (24.68/14.44)	YERHLRERTNLKRKLvH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     129.02|      39|     508|     143|     252|       3
---------------------------------------------------------------------------
  187-  229 (59.39/144.81)	RKLYPEgKLPHWLLGNLVSDFVDtFRP...TARINSICGRcsLLPV
  908-  949 (69.64/17.51)	HKKYPE.KLYFEGLAEQVNPPVQ.IQPqylPIYFGNVCLR..FLPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     159.90|      51|     665|      28|      88|       4
---------------------------------------------------------------------------
   28-   88 (83.45/78.81)	TPEDERTKLISCLGA.....FRQ....................FWSSLSQESHeqcvqwIVRFIHSQHSPKrisfLYDCL..AMAVET
  706-  783 (76.45/48.87)	TPHNWASHTLSCFPAplqvfFKQnnvpqesrfnlkknveeeyrKWKSMTNEND......IIAHFSVQGSPP....LFLCLlwKMLLET
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.78|      19|     665|     409|     427|       5
---------------------------------------------------------------------------
  409-  427 (37.90/19.55)	PVPD....INK.PQ.STHAFAMTCI
 1069- 1093 (23.87/10.05)	PFPNcdwrFNEfPNpAAHALHVTCV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.43|      24|      28|     600|     624|       6
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  600-  624 (40.55/31.28)	LH...TLLEMF.SYRMHHIQPHYrVQLLS
  626-  653 (30.88/18.00)	LHvesTALRLItALGSSEVQPQF.TRFLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      30|     338|     347|       7
---------------------------------------------------------------------------
  338-  347 (18.69/10.42)	IFFVLFQFAS
  371-  380 (19.45/11.17)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      31.88|      10|      31|     134|     143|       9
---------------------------------------------------------------------------
  134-  143 (15.58/ 9.71)	RDLLKVILEK
  163-  172 (16.30/10.50)	REVVAYILER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.47|      13|     177|     666|     679|      12
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  666-  679 (18.53/19.48)	LNRaLILTLARATH
  845-  857 (24.94/20.06)	LDR.LILCLAMRSH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     158.57|      50|     845|     268|     317|      14
---------------------------------------------------------------------------
  268-  317 (89.38/55.09)	LLRYVLE.QP.YSRDMVC...NMLGL..NKQHKQRCPVLEDQLVDLVVYAMERSETE
 1109- 1165 (69.18/40.94)	LLNVVLKsQPlVPRENITawmNAIGLiiTALPEPYWIVLHDCIVNVINSPSLTSETE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.51|      10|     375|     893|     907|      15
---------------------------------------------------------------------------
  877-  886 (17.69/13.59)	NDFRNRVSDF
  898-  907 (20.82/ 6.11)	NDWHTKHMSY
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP01984 with Med23 domain of Kingdom Metazoa

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