<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01930

Description Uncharacterized protein
SequenceMIRALQEAEDDEILDVILDIIKRDADVWTAMDLWPRLGDKLLDRHHVLERKGKEHPRLVQLLRVLAQKKRLTPDDEDEVEQLQTSIDKSTTPPGGIKLVDIFEVLPHILTTGKESKAISVAPALFRQCGSFSSWSLKWWMLIVDVVQKANTEQKPFLYHVISTHLSAVLGQHGDSLDDAVTSWLENLSAVNLVETFGKRSSGVLVRLLLFLISHHFLSTWVLLEKAVFPIWKHASPFALPPRKRLSSKQIQAITSTVNIIAQLLISPPLIPDFPPMSLKESLIVQASRQPVLQRLSVGILIQHLPLLVVFEQSKLLPDQISQRIDAILRNLAMTAEFKTAAFRNLNLLKDAFLAREWSGPGMDQGLEGKMTDVLKRIMSEKPTPEGQNVAEAKQTLNQLVHATLDRETTADDTDLLCEVFRGVDSMVTQEILAAGLERLATLLGHAIAAESQQQLETNIKSIDQLLRILDSMNNLPSQSVTEASVLNARHKLLDLLALALQTVERNLSTTRDGSDLLLPPGISPPQPSHLLKAVMGLLKFTLGSVGSENGSLTAPKPNFPHLAVCFLKAIFASDGFLDSSSAKIMADMLVYIIDCTSPQARLICQSALLAETASPHAQSILSSFPELSAALPYLSPVRRHMSLVTPDTADHASDSALPLDDRHWELFEYIGPPKRKIGPQDLFLASAPLKDASSIPITLFDPKITRDAPPNAGTMDAYDKPAEDGELSPVVNSASPAEEEEPRRSWETFASERNLGDGLAGEPAYAKQAATLVFSARDNDVPEAAPVKSFASQQPVVVVPSSTSPQKPKGKRSNSSGKDKVTGSNKDAPIAVEEDENDEDSEVEAPLSKKAKTAKNSAAGSGKSTTTAGKAPARKTTGGKGVSKKATGKSAKESGTGKAKGGRRKSQAE
Length909
PositionKinase
OrganismCryptococcus gattii serotype B (strain R265) (Filobasidiella gattii) (Cryptococcus bacillisporus)
KingdomFungi
Lineage
Aromaticity0.05
Grand average of hydropathy-0.213
Instability index47.73
Isoelectric point6.18
Molecular weight98869.94
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP01930
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.60|      33|      35|     823|     857|       1
---------------------------------------------------------------------------
  823-  857 (50.03/38.01)	GSNKDAPIAVEEDENDEDSevEAPLSKKA..KTAKNS
  860-  894 (49.56/31.41)	GSGKSTTTAGKAPARKTTG..GKGVSKKAtgKSAKES
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.16|      28|      35|     310|     338|       2
---------------------------------------------------------------------------
  310-  338 (43.00/24.18)	FEQSKLLPDQISQR......IDAILRNlAMTAEFK
  342-  375 (41.16/19.48)	FRNLNLLKDAFLARewsgpgMDQGLEG.KMTDVLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.16|      23|      90|     376|     405|       3
---------------------------------------------------------------------------
   63-   87 (32.48/18.23)	RVLAQKKrlTPDDEDEVEQLQT.......SID
  376-  405 (33.68/34.19)	RIMSEKP..TPEGQNVAEAKQTlnqlvhaTLD
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.63|      20|      38|     616|     653|       4
---------------------------------------------------------------------------
  622-  647 (27.82/40.73)	SSFP......ELsaaLPYLSPVRRHmslVTPD
  655-  680 (31.81/ 6.13)	SALPlddrhwEL...FEYIGPPKRK...IGPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.56|      26|      38|     512|     538|       5
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  512-  538 (43.51/27.90)	DGSdLLLPPGISPPQPSHLLKAVM...GLL
  549-  577 (44.05/23.73)	NGS.LTAPKPNFPHLAVCFLKAIFasdGFL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.76|      33|      39|     720|     753|       6
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  720-  753 (52.21/32.32)	KPAEDGELSPVVNSASPAEEEEPrRSWETFASER
  762-  794 (54.55/29.71)	EPAYAKQAATLVFSARDNDVPEA.APVKSFASQQ
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.34|      28|      48|     407|     434|       8
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  407-  434 (45.05/30.92)	ETTADDTDLLCEVFRGVDSMVTQEILAA
  456-  483 (44.30/30.28)	ETNIKSIDQLLRILDSMNNLPSQSVTEA
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.73|      20|      58|      35|      54|      10
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   35-   54 (36.94/23.88)	PRLGDKLLDRHHVLER...KGKE
   92-  114 (32.79/20.39)	PPGGIKLVDIFEVLPHiltTGKE
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP01930 with Med12 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AKQAATLVFSARDNDVPEAAPVKSFASQQPVVVVPSSTSPQKPKGKRSNSSGKDKVTGSNKDAPIAVEEDENDEDSEVEAPLSKKAKTAKNSAAGSGKSTTTAGKAPARKTTGGKGVSKKATGKSAKESGTGKAKGGRRKSQAE
2) APPNAGTMDAYDKPAEDGELSPVVNSASPAEEEEPRRSWETFASERNLGDGLAGEPA
766
708
909
764

Molecular Recognition Features

MoRF SequenceStartStop
1) NDEDSEVEAPLSKKAKTAKNSAAGSGKSTTTAGKAPARKTTGGKGVSKKATGKSAKESGTGKAKGGRRKSQAE
837
909