<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01927

Description Mediator of RNA polymerase II transcription subunit 6
SequenceMAQQVEEIEQDLSHIHWSWPEAIAANPARSLATPDLAMDYFAYSPFWDSKSNNNVLRTQRRIENPAYGHAEEKVELNAFMSGFEYVVAHSLPPDLFVIHRREVESSGKRDRITGAWFILHEKIYQCPTLFDVMSTRLKNATSLISKTLGTLSENRPPANPRTTTLWRSIPSSVPSQPDGAPSPSSNQANPDGEKQDGSLSVSSPLNRSDGKALPAGPDWHLFHALQATRASLASLETLAKTPAQTTNPREELKNIEIAMGSQLGGQNQSLSGKGPNVNGGTASVRSTSIPSVPKYSANHPNSVTGLISRIWSVAVYLGISTAATSTMEAGGSLLKSSGGDKSAPIAGSTVGASSALAGQAGRFQ
Length364
PositionHead
OrganismCryptococcus gattii serotype B (strain R265) (Filobasidiella gattii) (Cryptococcus bacillisporus)
KingdomFungi
Lineage
Aromaticity0.06
Grand average of hydropathy-0.412
Instability index53.29
Isoelectric point7.14
Molecular weight38929.97
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP01927
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     219.95|      55|      56|     138|     193|       1
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  138-  186 (80.21/37.08)	.......KNATSL.ISKTLG....TLSENRP.PANPRTTTLWRSIP...SSVPSQPD.GAPSPSSN
  188-  245 (72.88/34.30)	ANPDGE.KQDGSLsVSSPLN....R.SDGKAlPAGP.DWHLFHALQatrASLASLET.LAKTPAQT
  246-  302 (66.85/27.62)	TNPREElKNIEIA.MGSQLGgqnqSLSGKGP.NVNGGTASV.RS.....TSIPSVPKySANHPNS.
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Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP01927 with Med6 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) ASLETLAKTPAQTTNPREELKNIEIAMGSQLGGQNQSLSGKGPNVNGGTASVRSTSIPSVPKYSAN
2) ISKTLGTLSENRPPANPRTTTLWRSIPSSVPSQPDGAPSPSSNQANPDGEKQDGSLSVSSPLNRSDGKALP
233
144
298
214

Molecular Recognition Features

MoRF SequenceStartStop
NANANA