Description | Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MADAQRALTAAFPPPPPFWKHFTAENIEKLEKIKKESAATKTSPGKKWTPSELRALDVPPELRYLIPPEPPKEGAYTVFGELQNLSTNLPSLKEQGIEQLYPDAPADGKDDQNGGRALNHAYYLLKISKSLLLNFLEFVGILSIAPEEFEAKLGDLRNLFINAHHLLNLYRPHQARESLILMMEEQLESTRNQIQEMDDVKNRVERLLEQLTAEGLDAQSVPQELGNEANAVQFDSKTVEEARKLWELLNDEDE |
Length | 254 |
Position | Middle |
Organism | Talaromyces marneffei PM1 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Trichocomaceae> Talaromyces> Talaromyces sect. Talaromyces. |
Aromaticity | 0.07 |
Grand average of hydropathy | -0.587 |
Instability index | 46.57 |
Isoelectric point | 4.87 |
Molecular weight | 28782.18 |
Publications | PubMed=25330172 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364060 ECO:0000256 ARBA:ARBA00003669 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP01862 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 59.69| 15| 52| 3| 17| 1 --------------------------------------------------------------------------- 3- 17 (29.31/14.64) DAQRALTAAFPPPPP 57- 71 (30.38/15.39) DVPPELRYLIPPEPP --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) FTAENIEKLEKIKKESAATK 2) GKKWTPSELRALDVPPELRYLIP | 22 45 | 41 67 |
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