<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01846

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKRFFPRGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQVRTYWHYCGTPPSPSEFDDFSRDLCVQSLLEIMDMFCDRLSCHGKAEECISLCRALLSALTWLLRCAAFYAEKVKEPLEQAAAENQLKMCLERLEKVLSSTKNRALIHIAKLEETPSWSTVEQSLVKLGENLNNLGTSPLRSQADDCVSLIKSIPTMLSVHSEQLNKTGFPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQRIPSPLFVLEIWKACFVGLIECPEGTEELKWTAFTFLKMPQVLVKLKKYPQGDRDFTEDVNCAFEFLLKLTPLLDKADQRCKKGDGFLLTGPSLGSLRTADKENSPCLKSAENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFVKLNEFTKQITGEISKSGSVRALLFDISFLMLCHVAQTYGSEVILSDSNPPGEVPFFETWMLTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEVCLSISAAILEILNAWENGVLTFESIQKITDNIKGKVCSMAVCAVAWLVAHVRMLGLDEREKSLQMIRQLATPLYGENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGMDTIPYWNLLPPKKPIKEVLTSVFTKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLVKELLKETRKEHTLRAVELLYAIFCLDMQQLTLTLLGHILPNLLTDSSKWHTLMDPPGKALAKLSVWCALSSYSSHNKGQASARQKKRHREDIEDYISLFPLDDTQPSKLMRLLSSNEEDSNILSSPNRSMSSSLSASQLHTVSMRDPLNRVLANLFLLISSILGAKTAGTHTQFVQWFMEECVECLEQGSRGSILQFMPFTMVSELVKVSTMSSPKIVLAITDLSLPLGRRVAAKAIAAL
Length976
PositionTail
OrganismManacus vitellinus (golden-collared manakin)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Passeriformes> Pipridae> Manacus.
Aromaticity0.07
Grand average of hydropathy-0.018
Instability index48.28
Isoelectric point6.87
Molecular weight109304.24
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01846
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     182.49|      56|     115|       4|      60|       1
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    4-   60 (95.75/65.83)	VNLKQAILQA..WKERWSDYqWAINMKRFFPRGATWDILNLAEALLEQAMIGPSPNPLI
  121-  178 (86.74/54.86)	ISLCRALLSAltWLLRCAAF.YAEKVKEPLEQAAAENQLKMCLERLEKVLSSTKNRALI
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.82|      25|     222|     279|     310|       2
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  286-  310 (47.96/43.24)	WKACFVGLIECPEGTEELK...WTAFTF
  313-  340 (40.86/20.65)	MPQVLVKLKKYPQGDRDFTedvNCAFEF
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     194.40|      65|     287|     392|     559|       4
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  486-  558 (108.18/213.13)	MLCHVAQTygsevILSDS.......NPPGE.VPFFETW.MLTCMP..EEGKILNPDHPCFRPDstkVESLVAL..LNNSSEMKLVQ
  770-  847 (86.22/24.37)	LLGHILPN.....LLTDSskwhtlmDPPGKaLAKLSVWcALSSYSshNKGQASARQKKRHRED...IEDYISLfpLDDTQPSKLMR
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.66|      31|     124|      80|     115|       5
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   80-  115 (55.24/48.16)	GTPPSPSEFDDfsrdlCV...QSLLEIMDMFCDRLSCHG
  207-  240 (50.42/32.19)	GTSPLRSQADD.....CVsliKSIPTMLSVHSEQLNKTG
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      69.95|      21|      33|     346|     366|       9
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  346-  365 (30.45/16.50)	......PLLDKAD.QRCKKG.........DGFL......LTG
  366-  400 (20.83/ 9.07)	PslgslRTADKEN.SPCLKSaenaniqpnPGLI......LRA
  402-  432 (18.67/ 7.40)	P..tvtNILKTMDaDHSKSP.........EGLLgvlghmLSG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01846 with Med24 domain of Kingdom Metazoa
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