<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01834

Description Mediator of RNA polymerase II transcription subunit 23 (Fragment)
SequenceKTEVIEEAFPGMFMDTPEDERTKLISCLGAFRQFWSSLSQESHEQCVQWIVRFIHSQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVVAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAMCNSWKLDPTTLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAHSDNSKLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGNMRTPLPGTNCTASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAALPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSGESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPAPLQVFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIITHFSAQGSSPLFLCLLWKMLLDTDHINQIGFRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMSYHKKYPEKLYFEGLAEQVNPPVQIQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEGHLRERTNLKRKLVHAIIGSLKDNRPLGWCLSDTYLKCAMNPREENPWVPDDTYYCKLIGRLVDNILKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKEVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDCIVNVINSPSLTSETEWVGYPFQLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTESLIPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYEMLLNADRYSSHLNYMDPICDFLYHMKYMFTGDSVKDQVEKIICNLRPALKLRLRFITHISKMESAAVAQPPLSNGSPAQQPSQVPVNVALPVTQ
Length1356
PositionTail
OrganismManacus vitellinus (golden-collared manakin)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Passeriformes> Pipridae> Manacus.
Aromaticity0.10
Grand average of hydropathy-0.027
Instability index44.90
Isoelectric point7.47
Molecular weight155111.43
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01834
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.56|      13|      17|    1025|    1040|       1
---------------------------------------------------------------------------
 1025- 1038 (24.25/18.35)	RPLG.WCLSDTYLkC
 1043- 1056 (24.30/ 7.73)	REENpWVPDDTYY.C
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.12|      20|     127|     571|     591|       2
---------------------------------------------------------------------------
  571-  591 (33.53/25.79)	FISQLLPTV..FKSHAWGIlHTL
  698-  719 (36.59/23.33)	WCKDILQTImsFTPHNWAS.HTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.56|      16|      17|     982|     997|       3
---------------------------------------------------------------------------
  982-  997 (31.63/23.64)	YKFHDRPVTYLYNTL.H
  999- 1015 (24.93/16.84)	YEGHLRERTNLKRKLvH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     132.56|      41|     300|     924|     965|       4
---------------------------------------------------------------------------
  924-  965 (70.89/42.30)	LAEQVNPPVQIQPQYLPIY..FGNVCLRFLP.....VFDIVIHrFLELL
 1217- 1264 (61.67/32.47)	LTESLIPIVKTEFQLLYVYhlVGPFLQRFQQertrcMIEIGVA.FYEML
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.37|      25|     127|     157|     196|       6
---------------------------------------------------------------------------
  158-  184 (39.44/48.45)	LERNAclLPAYFAVTEIRK.LYPEGK.LP
  371-  397 (35.93/ 9.27)	IQKNA..LADFLPVMKLFDlLYPEKEcIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      32|     326|     335|       7
---------------------------------------------------------------------------
  326-  335 (18.69/ 9.55)	IFFVLFQFAS
  359-  368 (19.45/10.23)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     129.74|      40|     711|      17|      70|       8
---------------------------------------------------------------------------
   26-   70 (70.85/56.72)	SCLGA.....FRQ....................FWSSLSQESheqcvQWIVRFIHSQHSPKRISFLYDCL
  720-  784 (58.90/24.71)	SCFPAplqvfFKQnnvpqesrfnlkknveeeyrKWKSMTNEN.....DIITHFSAQGSSPLFLCLLWKML
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.94|      34|     602|     194|     235|       9
---------------------------------------------------------------------------
  194-  235 (45.93/51.08)	DF.VDTFRPTARINSIcGRCslLPVVNNsgaMCnsWKLDPTTL
  815-  849 (58.01/34.86)	DFlVYEFSTSAGGQQL.NKC..IEILND...MV..WKYNIVTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.89|      25|      43|     405|     429|      11
---------------------------------------------------------------------------
  405-  429 (47.13/32.39)	QSTHAF..........AMTCIWIHLNRKAHSDNSK
  439-  473 (37.76/24.43)	KLHHEFlqqslrnkslQMNDYKIALLCNAYSTNSE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01834 with Med23 domain of Kingdom Metazoa
Unable to open file!