<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01822
Description |
Mediator of RNA polymerase II transcription subunit 17 (Fragment) |
Sequence | GLVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVKDKKFMTLDPVVQDPLPPKQNPQFLQLISKKKSLAGAAQILLKGAERLSKSVAENQENKRQRDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFLHHGTFEVIKNTDIDLDKKIPEDYCPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPMPKSKPGSPHWQTKLETAQNVLLCKEIFAQLSREAVQIKSQIPHIVVKNQIISQPFPGLQLSISLCHSSNDKKSQKSASEKQNPEDHLYVLEHNLHQLIRECHKQTLSSTVMPHPASAPFGHKRMRLAGPQAFDKNDISSLQSNEGLLEKIIKQAKHIFLRRRTARTIDSLASRIEDPQIQAHWSNINDVYESSVKVLITSQGYEQICKSIQLQLNIGVEQIRVVHRDGRVITLSHQEQELQDFLLSQMSQHQVHAVQQLAKVMGWHVLSFSNHVGLGPVESIGNASAITVASPNGDYAISVRNGPESGSKVMVQFPRSQCKDLPKGDVLQDNKWNHLRGPFKEVQWNKMEGRNFVYKMELLMAALTPC |
Length | 566 |
Position | Head |
Organism | Struthio camelus australis |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi>
Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda>
Coelurosauria> Aves> Palaeognathae> Struthioniformes> Struthionidae>
Struthio.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.439 |
Instability index | 52.61 |
Isoelectric point | 9.28 |
Molecular weight | 63952.76 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP01822
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 290.90| 96| 220| 127| 234| 1
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127- 234 (142.29/126.10) RSAGSLFLHHGTFEVIKN..TDIDlDKKIPEDYCPLD......VQIPSDLEGSAYIKVSIQKQApDIG..DLGTVNLFKRPMPKSkpgspHWQTKLetaQNVLLCKeiFAQLSREAVQ
350- 455 (148.60/97.01) KQAKHIFLRRRTARTIDSlaSRIE.DPQIQAHWSNINdvyessVKVLITSQGYEQICKSIQLQL.NIGveQIRVVHRDGRVITLS.....HQEQEL...QDFLLSQ..MSQHQVHAVQ
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