<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01809

Description Mediator of RNA polymerase II transcription subunit 23 (Fragment)
SequenceKTEVIEEAFPGMFMDTPEDERTKLISCLSAFRQFWSSLSQDSHEQCVQWIVRFIHSQHSPKRISFLYDCLAMAVETGLLPPRLVCEALLNSDTLEWERTQLWALTFRLVRKIIGGVDYKGVRDLLKVILEKILTIPSTVSSAVVQQLLAAREVVAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAMCNSWKLDPSTLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFASLCLQCIPVPDITKPHSTHAFAMTCIWIHLNRKAHSDNSKLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGNVRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSLALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLDCFPAPLQVFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSIQGSPPLFLCLLWKMLLDTDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMSYHKKYPEKLYFEGLAEQVNPPVQIQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHGPVPSLYNTLHYYELQLRERPNLKRKLVHAIIGSLKDNRPLGWCLSDTYLKCAMNAREENPWVPDDAYYCKLIGRLVDNILPPVGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLDVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVINSPSLTSETEWVGYPFQLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLIPIVQTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYEMLLSADRCSAHLSHMDPICDFLYHMKYMFTGDSVKEQVEKIICNLRPALKLRLRFITHISKMEPAAVPQQALSNGSPAQQPSQVPVNVALPVTQ
Length1357
PositionTail
OrganismDryobates pubescens (Downy woodpecker) (Picoides pubescens)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Piciformes> Picidae> Picoides.
Aromaticity0.10
Grand average of hydropathy0.016
Instability index45.58
Isoelectric point7.47
Molecular weight154777.32
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01809
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.86|      11|     127|     569|     589|       1
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  578-  589 (18.77/29.92)	FKSHAWGIlHTL
  707-  717 (24.09/ 6.76)	FTPHNWAS.HTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.98|      33|     131|     897|     938|       2
---------------------------------------------------------------------------
  898-  934 (60.32/65.12)	LQNDWHTKHMS.........YHKKYpeklYFEG..LAEQVNPPV.QIQP
 1266- 1310 (44.66/21.30)	LSADRCSAHLShmdpicdflYHMKY....MFTGdsVKEQVEKIIcNLRP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.49|      19|      79|     759|     777|       4
---------------------------------------------------------------------------
  759-  777 (36.01/19.69)	NDIITHFSIQGSPPLFLCL
  836-  854 (35.48/19.29)	NDMVWKYNIVTLDRLILCL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     108.03|      30|      79|     418|     465|       6
---------------------------------------------------------------------------
  391-  416 (32.80/22.88)	.LQcIPVPDIT..KPHstHAF..........AMTCIWIH
  427-  460 (47.72/36.86)	KLQ.IPIPHSL..KLH..HEFLQqsLRNKslQMNDYKIA
  981- 1003 (27.51/ 6.98)	KFH.GPVP.SLynTLH..YYELQ..LRER..........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      31|     326|     335|       8
---------------------------------------------------------------------------
  326-  335 (18.69/10.81)	IFFVLFQFAS
  359-  368 (19.45/11.58)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      31.88|      10|      27|     122|     131|       9
---------------------------------------------------------------------------
  122-  131 (15.58/11.36)	RDLLKVILEK
  151-  160 (16.30/12.28)	REVVAYILER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.10|      24|     709|      17|      41|      10
---------------------------------------------------------------------------
   17-   41 (38.00/27.52)	PEDERTKLISCLSA.FRQfWSSLSQD
  734-  758 (36.10/21.00)	PQESRFNLKKNVEEeYRK.WKSMSNE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     160.59|      53|     861|     255|     309|      14
---------------------------------------------------------------------------
  255-  309 (90.60/53.70)	ALLRYVLE.QP.YSR.....DMvcNMLGL..NKQHKQRCPVLEDQLVDLVVYAMERSETE......EKFD
 1112- 1179 (69.99/35.61)	ALLDVVLKsQPlVPRenitaWM..NAIGLiiTALPEPYWIVLHDRIVSVINSPSLTSETEwvgypfQLFD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      63.77|      13|     568|     378|     390|      16
---------------------------------------------------------------------------
  378-  390 (23.15/11.57)	DFLPVMKLFASLC
  935-  945 (19.95/ 8.99)	QYLPIY..FGNVC
  947-  959 (20.68/ 9.58)	RFLPVFDIVIHRF
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01809 with Med23 domain of Kingdom Metazoa
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