<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01802

Description Mediator of RNA polymerase II transcription subunit 23 (Fragment)
SequenceKTEVIEEAFPGMFMDTPEDERTKLISCLGAFRQFWSSLSQESHEQCVQWIVRFIHNQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVVAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAMCNSWKLDPTTLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKYDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAHSDNSKLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGNMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSLALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPAPLQVFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMSYHKKYPEKLYFEGLAEQVNPPVQIQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERHLRERTNLKRKLVHAIIGSLKDNRPLGWCLSDTYLKCAMNAREDNPWIPDDTYYCKLIGRLVDNILLKICKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVINSPSLTSETEWVGYPFQLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLIPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYEMLLNADRYSSHLNYMDPICDFLYHMKYMFTGDSVKDQAEKIICNLRPALKLRLRFITHISKMEPAAVSQQPINNGSPAPQPSQVPVNVALPVTQ
Length1360
PositionTail
OrganismStruthio camelus australis
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Palaeognathae> Struthioniformes> Struthionidae> Struthio.
Aromaticity0.10
Grand average of hydropathy-0.028
Instability index45.09
Isoelectric point7.85
Molecular weight155890.59
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01802
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      73.18|      16|      38|    1017|    1032|       1
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 1017- 1032 (31.38/21.81)	IIGSLKDNRPLGWCLS
 1039- 1049 (15.50/ 6.56)	AMNAREDN.P..WI..
 1058- 1073 (26.31/16.94)	LIGRLVDNILLKICKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      32|     326|     335|       2
---------------------------------------------------------------------------
  326-  335 (18.69/10.46)	IFFVLFQFAS
  359-  368 (19.45/11.20)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.12|      20|     127|     571|     591|       3
---------------------------------------------------------------------------
  571-  591 (33.53/21.98)	FISQLLPTV..FKSHAWGIlHTL
  698-  719 (36.59/19.87)	WCKDILQTImsFTPHNWAS.HTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      31.88|      10|      28|     122|     131|       4
---------------------------------------------------------------------------
  122-  131 (15.58/ 9.62)	RDLLKVILEK
  151-  160 (16.30/10.40)	REVVAYILER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.65|      41|     711|      17|      76|       5
---------------------------------------------------------------------------
   26-   76 (67.57/66.45)	SCLGA.....FRQ....................FWSSLSQESHeqcvqwIVRFIHNQHSPKrisfLYDCL..AMAVET
  720-  787 (58.09/24.81)	SCFPAplqvfFKQnnvpqesrfnlkknveeeyrKWKSMTNEND......IITHFSMQGSPP....LFLCLlwKMLLET
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     123.33|      26|     711|     175|     217|       9
---------------------------------------------------------------------------
  175-  201 (44.84/20.90)	RKLYPEGKLPHWLLGNL..VSDFVDtFRP
  912-  936 (43.32/15.52)	HKKYPE.KLYFEGLAEQ..VNPPVQ.IQP
  962-  988 (35.17/31.50)	LELLPVSKSLETLLDHLggLYKFHD..RP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.84|      17|     294|     844|     876|      10
---------------------------------------------------------------------------
  824-  840 (29.21/35.10)	SAGGQQLNKCIEILNDM
  860-  876 (29.62/ 7.85)	SHEGNEAQVCYFIIQLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     132.84|      44|     864|     260|     305|      13
---------------------------------------------------------------------------
  260-  305 (74.11/54.51)	VLE.QP.YSRD.....MvcNMLGL..NKQHKQRCPVLEDQLVDLVVYAMERSETE
 1120- 1172 (58.74/36.02)	VLKsQPlVPREnitawM..NAIGLiiTALPEPYWIVLHDRIVSVINSPSLTSETE
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01802 with Med23 domain of Kingdom Metazoa
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