<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01798
Description |
Mediator of RNA polymerase II transcription subunit 20 (Fragment) |
Sequence | VAQVPVAEGKSVQQTVEMLTRKLELLGAEKQGTFCVDCETYHTAASTMGNQGQTGKLMYVMHNSEYPLSCFALFENGPCLIADANFDILMVKLKGFFQNAKANKIESRGTRYQYCDFLVKVGTVTMGPSARGISVEVEYCPCVIANDCWNLLMEFMQSFMGSHTPGIPSVFGTKHDSIYSPADTMVQYMELFNKIRKQQQVPVAGIR |
Length | 207 |
Position | Head |
Organism | Struthio camelus australis |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi>
Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda>
Coelurosauria> Aves> Palaeognathae> Struthioniformes> Struthionidae>
Struthio.
|
Aromaticity | 0.10 |
Grand average of hydropathy | -0.071 |
Instability index | 31.43 |
Isoelectric point | 6.47 |
Molecular weight | 22996.35 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364152
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP01798
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 53.52| 17| 30| 89| 115| 1
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89- 105 (27.37/ 7.31) LMVKLKGFFQNAKANKI
117- 133 (26.15/22.00) FLVKVGTVTMGPSARGI
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 57.18| 14| 61| 75| 88| 3
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75- 88 (26.43/18.91) ENGPCLIADANFDI
138- 151 (30.75/23.07) EYCPCVIANDCWNL
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