<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01794

Description Mediator of RNA polymerase II transcription subunit 24 (Fragment)
SequenceLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSTVLTAISKFDDFSRDLCVQSLLEIMDMFCDRLSCHGKAEECIGLCRALMSALNWLLRCAAFYAEKVKETLEQAAAESQLKMCLERLEKMLSSTKNRALIHIAKLEETSSWSAVEQSLIKLGENLSSLSNSPLRSQADDCVSLIKSIPTMLSVHTEQLNKTGFPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQRIPSPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYPQGEKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCTSLLLQECSKQGLLSEANMTNLIAKRTADREHAPRLKSAENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFTKHISGEGSKAASVRALLFDISFLMLCHVAQTYGSEVILSESSPAGEVPFFETWMLTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENSVLTFESIQKITDNIKGKVCSMAVCAVAWLVAHVRMLGLDEREKSLQMIRQLATPLYGENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGMDTIPYWNLLPPKKPIKEVLTSVFTKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLVKELLKETRKEHTLRAVELLYAIFCLDMQQLTLTLLGHILPNLLTDSSKWHTLMDPPGKALAKLSVWCALSSYSSHNKGQASARQKKRHREDIEDYISLFPLDDTQPSKLMRLLSSNEEDANILSSPNRSMSSSLSASQLHTVSMRDPLNRVLANLFLLISSILGAKTAGTHTQFVQWFMEECVDCLEQGSRGSILQFMPFTMVSELVKVSTMSSPKIVLAITDLSLPLGRRVAAKAIAAL
Length945
PositionTail
OrganismStruthio camelus australis
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Palaeognathae> Struthioniformes> Struthionidae> Struthio.
Aromaticity0.06
Grand average of hydropathy0.034
Instability index48.99
Isoelectric point6.47
Molecular weight105250.63
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01794
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.50|      28|     221|     513|     548|       1
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  513-  548 (36.93/43.55)	LVALLNNSSemklvqmKWHeACLSISAAILEILNAW
  744-  771 (50.57/33.80)	LPNLLTDSS.......KWH.TLMDPPGKALAKLSVW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      90.91|      26|     196|     280|     316|       2
---------------------------------------------------------------------------
  253-  278 (35.44/14.82)	PEG....TEELKwTAFTF.L...KIPQVLVK..LKK
  280-  309 (41.90/30.12)	PQGekdfTEDVN.CAFEFLL...KLTPLLDK..ADQ
  322-  345 (13.58/17.02)	...........E.CSKQGLLseaNMTNLIAKrtADR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.42|      29|     302|     105|     136|       3
---------------------------------------------------------------------------
  105-  133 (47.07/37.49)	LEQAAAESQLKMCLERLEKMLSSTKNRAL
  139-  167 (47.35/28.24)	LEETSSWSAVEQSLIKLGENLSSLSNSPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.85|      21|     677|     218|     241|       8
---------------------------------------------------------------------------
  218-  241 (33.52/28.13)	P..LVEQLMMVKRMqriPSPLFVLEI
  904-  926 (31.33/18.04)	PftMVSELVKVSTM...SSPKIVLAI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01794 with Med24 domain of Kingdom Metazoa
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