<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01782
Description |
Mediator of RNA polymerase II transcription subunit 17 (Fragment) |
Sequence | KQVQGVGLDGSETYLQPLSMSQNLARLAQRIDFSQGSGSEEDEPGSAGRPWAEPGEAEDEEALVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVKDKKFMTLDPVVQDPLPPKQNPQFLQLISKKKSLAGAAQILLKGAERLSKSVAENQENKRQRDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFEVIKNTDIDLDKKIPEDYCPLDVQIPSDLEGSAYIKVSIQKQAPDIGDIGTVNLFKRPMPKSKPGSPHWQTKLETAQNVLLCKEIFAQLSREAVQIKSQIPHIVVKNQIISQPFPGLQLSISLCHSSNDKKSQKSASEKQNPEDHLYVLEHNLHQLIRECHKQTLSSTVMPHPASAPFGHKRMRLAGPQAFDKNEISSLQSNEGLLEKIIKQAKHIFLRRRTARTIDSLASRIEDPQIQAHWSNINDVYESSVKVLITSQGYEQICKSIQLQLNIGVEQIRVVHRDGRVITLSHQEQELQDFLLSQMSQHQVHAVQQLAKVMGWHVLSFSNHVGLGPVESIGNASAITVASPNGDYAISVRNGPESGSKVMVQFPRSQCKDLPKGDVLQDSKWNHLRGPFKEVQWNKMEGRNFVYKMELLMAALTPC |
Length | 627 |
Position | Head |
Organism | Dryobates pubescens (Downy woodpecker) (Picoides pubescens) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi>
Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda>
Coelurosauria> Aves> Neognathae> Piciformes> Picidae> Picoides.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.492 |
Instability index | 53.93 |
Isoelectric point | 8.67 |
Molecular weight | 70455.60 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP01782
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 54.17| 16| 104| 14| 29| 1
---------------------------------------------------------------------------
14- 29 (29.09/16.15) YLQPLSMSQNLARLAQ
121- 136 (25.07/12.99) FLQLISKKKSLAGAAQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 391.07| 105| 220| 188| 295| 2
---------------------------------------------------------------------------
188- 295 (172.50/108.91) RSAGSLFPHHGTFE......VIKN..TDIDlDKKIPEDYCPLD......VQIP....SDLEGSAYIKVSIQKQAP.DIG..DIGTVNLFK..R............PMPKSKP.GspHWQTKLETAQNVLLCKEIFAQLSREAVQ
297- 405 (83.37/44.43) .............KsqiphiVVKN........QIISQPFPGLQ......LSISlchsSN..DKKSQKSASEKQNPeDHL..YVLEHNLHQliRechkqtlsstvmPHPASAPfG..HKRMRLAGPQ.AFDKNEISSLQSNEGL.
411- 516 (135.20/76.53) KQAKHIFLRRRTAR......TIDSlaSRIE.DPQIQAHWSNINdvyessVKVL....ITSQGYEQICKSIQLQL..NIGveQIRVVHRDG..R............VITLS......HQEQEL...QDFLLSQ..MSQHQVHAVQ
---------------------------------------------------------------------------
|