<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01731

Description Mediator of RNA polymerase II transcription subunit 23 (Fragment)
SequenceKTEVIEEAFPGMFMDTPEDERTKLISCLGAFRQFWSSLSQESHEQCVQWIVRFIHSQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVVAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAMCNSWKLDPTTLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAHSDNSKLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGNMRISLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPAPLQVFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENEIIAHFSVQGSATLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMSYHKKYPEKLYFEGLAEQVNPPVQIQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYETHLRERTNLKRKLVHAIIGSLKDNRPLGWCLSDTYLKCAMNPREENPWVPDDTYYCKLIGRLVDNILLKVCIKLCQCKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVINSPSLTSETEWVGYPFQLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLIPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYEMLLNADRYSSHLNYMDPICDFLYHMKYMFTGDSVKDQVEKIICNLRPALKLRLRFITHISKMESAAVPQQPLSNGSPAQQPSQVPVNVALPVTQ
Length1366
PositionTail
OrganismOpisthocomus hoazin (Hoatzin) (Phasianus hoazin)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Opisthocomiformes> Opisthocomidae> Opisthocomus.
Aromaticity0.10
Grand average of hydropathy-0.010
Instability index44.12
Isoelectric point7.84
Molecular weight156431.26
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01731
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      31|     326|     335|       1
---------------------------------------------------------------------------
  326-  335 (18.69/11.26)	IFFVLFQFAS
  359-  368 (19.45/12.05)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.79|      24|      43|     588|     612|       2
---------------------------------------------------------------------------
  588-  612 (41.11/30.86)	LHTL..............LEMFSYRM......HHIQPHYrVQLLS
  614-  657 (24.69/12.41)	LHSLaavpqtnqnqlhlcVESTALRLitalgsSEVQPQF.TRFLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.31|      25|     611|     684|     747|       3
---------------------------------------------------------------------------
   16-   42 (39.34/ 8.57)	TPEDERTKLISCLGA.....FRQfwSSLSQES
  710-  739 (43.97/16.58)	TPHNWASHTLSCFPAplqvfFKQ..NNVPQES
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.29|      18|     611|     684|     707|       4
---------------------------------------------------------------------------
  684-  707 (23.50/28.69)	VTDF.......FTGsDSIqgtwcKDILQTIM
 1290- 1314 (27.79/13.78)	ICDFlyhmkymFTG.DSV.....KDQVEKII
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.33|      11|      32|    1071|    1081|       5
---------------------------------------------------------------------------
 1071- 1081 (23.25/15.26)	CIKLCQCKSPG
 1105- 1115 (20.08/12.10)	CVELMALAVPG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.03|      26|     299|     908|     955|       6
---------------------------------------------------------------------------
  390-  415 (51.97/17.68)	YPEK.......ECIPVPDINKPQSTHA.FAMTCI
  915-  948 (39.05/54.78)	YPEKlyfeglaEQVNPPVQIQPQYLPIyFGNVCL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.28|      27|     127|     157|     195|       9
---------------------------------------------------------------------------
  163-  194 (41.06/51.52)	CLLPAYFAVTeirkLYPEGKLPhW.........LLGNLVSD
 1030- 1065 (45.22/19.91)	CLSDTYLKCA....MNPREENP.WvpddtyyckLIGRLVDN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.59|      22|      35|     824|     845|      11
---------------------------------------------------------------------------
  824-  845 (40.10/30.78)	SAGGQQLNKCIEILNDMVWKYN
  860-  881 (38.49/29.19)	SHEGNEAQVCYFIIQLLLLKPN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.37|      15|     872|      97|     114|      14
---------------------------------------------------------------------------
   97-  114 (22.03/20.78)	ERTQlwaLTFKLVRKIIG
 1005- 1019 (27.34/15.34)	ERTN...LKRKLVHAIIG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01731 with Med23 domain of Kingdom Metazoa
Unable to open file!