<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01701

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKRFFPRGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSTVLTAISKFDDFSRDLCVQSLLEIMDMFCDRLSCHGKAEECIGLCRALMSALNWLLRCAAFYAEKVKETLEQVAAESQLKMCLERLAKMLSSTKNRALIHIAKLEETSSWSTVEQSLVKLGENLNSLSSSPLRSQADDCISLIKSIPTMLSVHSEQLNKTGFPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQHIPSPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYPQGEKDFTEELNCAFECLLKLTPLLDKADQRCNCNCMNLLLQECSKQGLLSEANMTNLIAKRAADREHAPRLKSAENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFTKHITGEGSKGASVRALLFDISFLMLCHVAQTYGSEVILSESNPADEVPFFETWMLTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENSVLTFESIQKITDNIKGKVCSMAVCAVAWLVAHVRMLGLDEREKSLQMIRQLATPLYSENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGMDTIPYWNLLPPKKPIKEVLTSVFTKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLVKELLKETRKEHTLRAVERLYAIFCLDMQQLTLTLLGHILPNLLTDSSKWHTLMDPPGKALAKLSVWCALSSYSSHNKGQASTRQKKRHREDIEDYISLFPLDDTQPSKLMRLLSSNEEDANILSSPNRSMSSSLSASQLHTVSMRDPLNRVLANLFLLISSILGAKTAGTHTQFVQWFMEECVDCLEQGSRGSILQFMPFTMVSELVKVSTMSSPKIVLAITDLSLPLGRRVAAKAIAAL
Length986
PositionTail
OrganismEgretta garzetta (Little egret)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Pelecaniformes> Ardeidae> Egretta.
Aromaticity0.07
Grand average of hydropathy0.003
Instability index49.46
Isoelectric point7.07
Molecular weight110451.72
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01701
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.06|      17|     186|     158|     184|       2
---------------------------------------------------------------------------
  158-  174 (27.54/25.20)	CLERLAKMLSSTKNRAL
  192-  208 (26.52/ 6.67)	SLVKLGENLNSLSSSPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      92.32|      26|     186|     321|     352|       3
---------------------------------------------------------------------------
  294-  319 (35.92/16.33)	PEG....TEELKwTAF.TFL...KIPQVLVK..LKK
  321-  350 (42.87/31.46)	PQGekdfTEELN.CAFECLL...KLTPLLDK..ADQ
  363-  386 (13.53/ 6.02)	...........E.CSKQGLLseaNMTNLIAKraADR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01701 with Med24 domain of Kingdom Metazoa
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