<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01680

Description Mediator of RNA polymerase II transcription subunit 26 (Fragment)
SequenceGGVKPVRLKERKLTFDPMTGQIKPLTQKDPLQVEIPALTEQHRTETEKQEQKPNLQSPFEQTNWEELSRNEIIQSYLNRQSSLLSSSGVQTPGAHYFMSEYLKQEESTRKEARKTHVLAPNSKPTDLPGVTREVTSDDLNRIREHNWPGVNGCYDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length187
PositionUnknown
OrganismEgretta garzetta (Little egret)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Pelecaniformes> Ardeidae> Egretta.
Aromaticity0.07
Grand average of hydropathy-0.970
Instability index53.21
Isoelectric point5.59
Molecular weight21476.66
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP01680
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.55|      15|      17|      41|      57|       2
---------------------------------------------------------------------------
   41-   57 (20.43/17.84)	QhrTETEKQEQKPNLQS
   61-   75 (26.12/15.04)	Q..TNWEELSRNEIIQS
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP01680 with Med26 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) TRKEARKTHVLAPNSKPTDLPGVTREVTSDDLNRI
2) VRLKERKLTFDPMTGQIKPLTQKDPLQVEIPALTEQHRTETEKQEQKPNLQSPFEQTNW
108
6
142
64

Molecular Recognition Features

MoRF SequenceStartStop
1) GVKPVRLKERKLTFDPMTGQI
2) HYFMS
3) LNILPYVCL
2
95
178
22
99
186