<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01624

Description Mediator of RNA polymerase II transcription subunit 23 (Fragment)
SequenceVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSSFPAPLQVFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIITHFSAQGSSPLFLCLLWKMLLDTDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMSYHKKYAEKLYFEGLAEQVNPPVQIQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERHLRERTNLKRKLVHAIIGSLKDNRPLGWCLSDTYLKYAMNAREENPWVPDDAYYCKLIGRLVDNILKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGEDVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVINSPSLTSETEWVGYPFQLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLIPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYEMLLNADRYSSHLNYMDPICDFLYHMKYMFTGDSVKDQVEKIICNLRPALKLRLRFITHISKMEPAAVPQQPLNNGSPAQQPSQVPVNVALPVTQ
Length725
PositionTail
OrganismCuculus canorus (common cuckoo)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Cuculiformes> Cuculidae> Cuculus.
Aromaticity0.11
Grand average of hydropathy-0.101
Instability index48.76
Isoelectric point6.65
Molecular weight83572.46
Publications

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP01624
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.20|      16|      19|     351|     366|       1
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  351-  366 (31.52/19.91)	YKFHDRPVTYLYNTL.H
  368-  384 (24.68/14.09)	YERHLRERTNLKRKLvH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.14|      12|      19|     391|     404|       2
---------------------------------------------------------------------------
  391-  404 (20.48/15.77)	KDNRPlgWCLSDTY
  412-  423 (24.66/12.46)	REENP..WVPDDAY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.78|      19|      19|     541|     559|       3
---------------------------------------------------------------------------
  541-  559 (36.83/23.99)	YPFQLFDFTACHQSYSEMS
  562-  580 (32.95/20.70)	YTLALAHAVWHHSSIGQLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.66|      16|      21|     288|     303|       8
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  288-  303 (28.03/17.86)	LYFEGLAEQVNPPVQI
  310-  325 (29.64/19.32)	IYFGNVCLRFLPVFDI
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP01624 with Med23 domain of Kingdom Metazoa

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