<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01608

Description Transcription elongation factor A protein 1 (Fragment)
SequenceLLQSTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTDKDSEEKKKEPASSSQNSPEAREESSSSSNSSSRKEEGSAPSNSFIPSFPRAPSTSDSVRMKCREMLSAALRTGDDYIAIGADEEELGSQIEEDILSPIFQELKNTDMKYKNRVRSRIANLKDAKNPNLRKNVLCGNIPPDKFAKMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWK
Length265
PositionUnknown
OrganismCuculus canorus (common cuckoo)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Cuculiformes> Cuculidae> Cuculus.
Aromaticity0.04
Grand average of hydropathy-0.908
Instability index59.89
Isoelectric point8.58
Molecular weight29549.95
Publications

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:InterPro
GO - Biological Function
translation elongation factor activity	GO:0003746	IEA:UniProtKB-KW
zinc ion binding	GO:0008270	IEA:InterPro
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP01608
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.21|      23|      25|      50|      74|       1
---------------------------------------------------------------------------
   50-   72 (38.46/19.75)	KKKEPASSSQNS..PE.AREESSSSS
   76-  101 (31.74/10.39)	SRKEEGSAPSNSfiPSfPRAPSTSDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     130.62|      29|      79|     152|     180|       2
---------------------------------------------------------------------------
  152-  180 (47.22/31.93)	K..YKNRVRSRIANLKDAKNPNLRKNVL..CGN
  200-  231 (38.34/24.64)	KemRKNLTKEAIREHQMAKTGGTQTDLF.tCGK
  233-  262 (45.05/30.15)	K..KKNCTYTQV.QTRSADEPMTTFVVCneCGN
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP01608 with Med26 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) LLDGPSTDKDSEEKKKEPASSSQNSPEAREESSSSSNSSSRKEEGSAPSNSFIPSFPRAPSTSDSVRMKCREM
37
109

Molecular Recognition Features

MoRF SequenceStartStop
1) SEEKKKEP
2) TSLAKSLIKSWKKLLDG
47
24
54
40