<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01605

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKRFFPRGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSTVLTAISKFDDFSRDLCVQSLLEIMDMFCDRLSCHGNAEECIGLCRALMSALSWLLRCTAFYAEKVKETLEQAGAESQLKMCLERLEKMLSSTKNRALIHIAKLEEISSWNAVEQALVELGENLNSLSNSPLRSQADNCVSVIKSIPTMLSVRSEQLNKTGFPTVHAVVLLEGTMNLTGEIQPLVEQLMMVKRMQRIPTPLFMLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKNYHQGEKDFTEDVNCAFEFLLKLTPLLNKADQRCNCNCMSLLLQECSKQGLLSEANMDNLITKRTADREHAPHLKSAENANIQPNPRLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFAQKFIKLNEFTKDISGESSKGASVRALLFDISFLMLCHVAQTYGSEVILSESSPAGEVPFFETWMLTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENSVLTFESIQKITDNIKGKVCSMAVCAVAWLVAHVRMLGLDEREKSLQMIRQLATPLYSENTLQFYNERVVIMSSILEHMCVDVLQQTATQIKFPSTGMDTIPYWNLLPPKKPIKEVLMSVFTKVLEKGWVDSRSIHIFNTLLHMGGVYWFCNNLVKELLKETRKEHTLRAVELLYAIFCLDMQQLTLTLLGHILTNLLTDSSKWHTLMDPPGKALAKLSVWCALSSYSSHHKGQASARQKKRHREDIEDYISLFPLDDAQPSKLMRLLSSNEEEANILSSPNRSMSSSLSASQLHAVSMRDPLKRVLANLFLMSSILGAKTAGTHTQFVQWFMEECVDCLEQGSHSSILQFMPFSMVSELVKVSTMSSPKIVLAITDLSLPLGRRVAAKAIAAL
Length985
PositionTail
OrganismCuculus canorus (common cuckoo)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Cuculiformes> Cuculidae> Cuculus.
Aromaticity0.07
Grand average of hydropathy0.013
Instability index50.62
Isoelectric point6.68
Molecular weight110474.71
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01605
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     150.00|      49|      64|     863|     913|       1
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  863-  913 (71.66/55.18)	EEEANILSSPNRS.....MSSSLSASQLHAVSMRDPlKRVLAnLFLMSSILGAKTA
  925-  978 (78.34/51.00)	EECVDCLEQGSHSsilqfMPFSMVSELVKVSTMSSP.KIVLA.ITDLSLPLGRRVA
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     137.86|      43|      66|     478|     525|       2
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  478-  525 (64.38/52.20)	ESSKGASVRALLFDISFLMLChvaQTYGSEVILSESSPAGEVpfFETW
  547-  589 (73.48/44.24)	DSTKVESLVALLNNSSEMKLV...QMKWHEACLSISAAILEI..LNAW
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.75|      13|      64|     343|     370|       3
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  207-  219 (24.73/ 6.54)	PLRSQAD.....NCVSVI
  343-  360 (19.02/40.01)	PLLNKADqrcncNCMSLL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     203.35|      72|     141|     242|     331|       4
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  242-  331 (96.69/117.52)	HAvVLLEGTMNltGEIQPlVEQLMMvkRMQriPTplfMLEIWKACFVGLIESPEGT.....EELKWTAFTFL.kipqvlvKLKNYHQ...GEKDFTEDV
  388-  475 (106.66/73.85)	HA.PHLKSAEN..ANIQP.NPRLIL..RAE..PT...VTNILKTMDADHSKSPEGLlgvlgHMLSGKSLDLLlaaaaatgKLKSFAQkfiKLNEFTKDI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01605 with Med24 domain of Kingdom Metazoa
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