Description | Mediator of RNA polymerase II transcription subunit 9 |
Sequence | MDKDSQDVHQVLNELKNKFQEMRKLVSSMPGIGVSPEQQQQQLQNLREQVRTKNELLQKYKSLCMFEIPKE |
Length | 71 |
Position | Middle |
Organism | Corvus brachyrhynchos (American crow) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Passeriformes> Corvoidea> Corvidae> Corvus. |
Aromaticity | 0.04 |
Grand average of hydropathy | -0.999 |
Instability index | 68.68 |
Isoelectric point | 7.87 |
Molecular weight | 8418.60 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364145 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP01591 No repeats found No repeats found |
MoRF Sequence | Start | Stop |
1) MDKDSQDVHQVLNELKNKFQEMRKLVSSMPGIGVSPE 2) QQLQNLREQVRTKNELLQKYKSLCMFEIPKE | 1 41 | 37 71 |
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