<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01576

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKRFFPRGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSTVLTAISKFDDFSRDLCVQSLLEIMDMFCDRLSCHGKAEECISLCRALLSALTWLLRCAAFYAEKVKEPLEQAAAENQLKMCLERLEKVLSSTKNRALIHIAKLEETSSWSTVEQSLVKLGENLNNLGSSPLRSQADDCVSLIKSIPTMLSVHSEQLNKTGFPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQRIPSPLFVLEIWKACFVGLIECPEGTEELKWTAFTFLKMPQVLVKLKKYPQGDKLTPLLDKADQRCNCNCMSLLLQECSKQGLLSEANMNNLIDKRAADKENSPSLKSAENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFVKLNEFTKQITGEISKSGPVRALLFDISFLMLCHVAQTYGSEVILSDSNPPGEVPFFETWMLTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEVCLSISAAILEILNAWENGVLTFESIQKITDNIKGKVCSMAVCAVAWLVAHVRMLGLDEREKSLQMIRQLATPLYGENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGMDTIPYWNLLPPKKPIKEVLTGVFTKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLVKELLKETRKEHTLRAVELLYAIFCLDMQQLTLTLLGHILPNLLTDSSKWHTLMDPPGKALAKLSVWCALSSYSSHNKGQASARQKKRHREDIEDYISLFPLDDTQPSKLMRLLSSNEEDSNILSSPNRSMSSSLSASQLHTVSMRDPLNRVLANLFLLISSILGAKTAGTHTQFVQWFMEECVECLEQGSRGSILQFMPFTMVSELVKVSTMSSPKIVLAITDLSLPLGRRVAAKAIAAL
Length971
PositionTail
OrganismCorvus brachyrhynchos (American crow)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Passeriformes> Corvoidea> Corvidae> Corvus.
Aromaticity0.07
Grand average of hydropathy0.001
Instability index49.25
Isoelectric point7.23
Molecular weight108570.62
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01576
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.88|      26|      28|     444|     469|       1
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  444-  469 (43.44/30.18)	KS..FARKFVKLNEFTKQITGEI..SKSGP
  471-  500 (36.44/24.10)	RAllFDISFLMLCHVAQTYGSEVilSDSNP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     301.80|      98|     119|       4|     116|       2
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    4-  111 (157.39/162.68)	VNLKQAILQA..WKERWSDYqWAINMKRFFPRGATWDILNLAEALLEQAMIGPSPNPLI.LSYLKyaissQMVSYSTVLTAISKFDDFSRDL...........CVQSLLEIMDMfcdrLSCH
  118-  229 (144.41/108.37)	ISLCRALLSAltWLLRCAAF.YAEKVKEPLEQAAAENQLKMCLERLEKVLSSTKNRALIhIAKLE.....ETSSWSTVEQSLVKLGENLNNLgssplrsqaddCVSLIKSIPTM....LSVH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     158.61|      59|     222|     276|     337|       3
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  276-  307 (43.45/22.00)	.....................................................................................................................................................................................................PLF.VLEIWKACFVGLIEC.PEGTEELKWTAFTF
  308-  337 (20.07/17.26)	LKMpQVLVKLKKYPQGDKLTPLldKADQRC.........................................................................................................................................................................................................
  505-  529 (28.20/11.38)	..............................ncncmslllqecskqgllseanmnnlidkraadkenspslksaenaniqpnpglilraeptvtnilktmdadhskspegllgvlghmlsgksldlllaaaaatgklksfarkfvklneftkqitgeisksgpvrallfdisflmlchvaqtygsevilsdsnppgevPFF...ETW......MLTCmPEEGKILNPDHPCF
  534-  592 (66.88/39.15)	TKV.ESLVALLNNSSEMKLVQM..KWHEVC..................................................................................................................................................................lsisaAILeILNAWENGVLTFESI.QKITDNIK......
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01576 with Med24 domain of Kingdom Metazoa
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