<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01571

Description Cyclin-dependent kinase 19
SequenceMTKSRRNRPLGRNRPALVDSTGQASPDPATDDLEMRASPGEVSPGLAIRRVEPLSPGQEHLGLAVTIGNLEAQSLVEVCMVRTARAGTPPPLMEAFLDSCSICDASFPDPAEACISFLQEGMLRRSTSSVLDSSLELHSRVDLPAELLTQQEQAEPTEAEPKAAGPAPAQTEVPPVECVPAPPAAPSPALVPQPEPAPGAPSPPVTRAESDSLTSTGSVASKGRTLSTQWTELQVNSRNAALQVSRSHMEAVHPDQHLSHLRGERHRTQLIHLEDKFSSNSGLFSLKIPEGLRVWTSSVGGSRLFSRRKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDEPEEKGDKNQQQQQNQHQQPTAPPPQAAAPPQPPPQQQSNTQTNGTTGVVAAGVGGAAAGLQHSQDSGLNQVPPNKKPRLGPSGASSGGPVIPSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSAQFHPSHQAHRY
Length767
PositionKinase
OrganismFukomys damarensis (Damaraland mole rat) (Cryptomys damarensis)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Hystricomorpha> Bathyergidae> Fukomys.
Aromaticity0.06
Grand average of hydropathy-0.538
Instability index64.16
Isoelectric point6.84
Molecular weight84651.69
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01571
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.64|      14|      16|      34|      48|       2
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   34-   48 (21.06/14.60)	EmRASPGEVSPGLAI
   52-   65 (25.58/12.89)	E.PLSPGQEHLGLAV
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.08|      15|      17|     725|     741|       3
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  727-  741 (27.13/22.53)	SSRLNYQSSVQGSSQ
  743-  757 (26.94/13.57)	QSTLGYSSSSQQSAQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.65|      16|      17|     584|     599|       4
---------------------------------------------------------------------------
  584-  599 (27.33/16.89)	DPTKRITSEQALQDPY
  603-  618 (29.32/18.70)	DPLPTLDVFAGCQIPY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.91|      17|      17|     243|     259|       5
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  243-  259 (29.37/21.93)	QVSRSHMEAVHPDQHLS
  262-  278 (28.54/21.07)	RGERHRTQLIHLEDKFS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.07|      14|      18|      79|      95|       6
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   79-   95 (19.09/17.63)	CMVrtARAGTPPPlMEA
  100-  113 (27.98/13.53)	CSI..CDASFPDP.AEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     151.84|      40|      40|     452|     491|       7
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  393-  412 (22.91/ 9.37)	................VKSLLYQ....ILDGIHYLHA..N.WV
  413-  442 (31.97/15.71)	L........hrDLKPANILVMGEGPE.....RGRVKIADMgFA
  445-  484 (71.11/43.13)	FNSPLKPLA..DLDPVVVTFWYRAPELLLGARHYTKAIDI.WA
  485-  506 (25.85/11.43)	IGCIFAELL..TSEPI...FHCRQEDI................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.33|      30|     463|     185|     220|       8
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  185-  220 (49.15/33.02)	APSPALVPQPEPAPGAPSPPVTRAesdsltSTGSVA
  649-  678 (56.18/27.07)	APPPQAAAPPQPPPQQQSNTQTNG......TTGVVA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.65|      33|     167|     118|     152|      10
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  118-  152 (46.74/41.46)	LQEGmLRRSTSSVLDSSLeLHSRVDLPAELLTQQE
  288-  320 (58.91/41.04)	IPEG.LRVWTSSVGGSRL.FSRRKDEKEYALKQIE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.67|      13|      32|     679|     691|      11
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  679-  691 (23.38/12.15)	AGVGGAA..AGLQHS
  712-  726 (20.29/ 9.67)	ASSGGPVipSDYQHS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01571 with CDK8 domain of Kingdom Metazoa
Unable to open file!