<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01555

Description Mediator of RNA polymerase II transcription subunit 23 (Fragment)
SequenceFDRMFMDTPEDEKTKLISCLGAFRQFWSGLSQESHEQCIQWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKAILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNDLADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQNGNSKLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTSCLASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHTKSTVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIITHFSIQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERYLRNRDHLKRKLVHAIIGSLKDNRPQGWCLSDTYLKNVMNPREDNPWVPDDSYYCKLIGRLVDNILRSVTFCRRQ
Length1068
PositionTail
OrganismFukomys damarensis (Damaraland mole rat) (Cryptomys damarensis)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Hystricomorpha> Bathyergidae> Fukomys.
Aromaticity0.10
Grand average of hydropathy-0.080
Instability index41.32
Isoelectric point8.46
Molecular weight122948.45
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01555
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     483.08|     154|     168|     647|     813|       1
---------------------------------------------------------------------------
  647-  705 (57.93/21.85)	.................................................................................................................................FL.SDPKTVLSAESEELNRALILTLARATHVTDFFTGS..DSI.QGTWC.KD.ILQTIMSFTPHN
  706-  874 (198.79/133.04)	WASHTLSCFPGPLQAFFKQNNVpQESRFNLKKNVEEEYRkWKSMTNENDiiTHFSIQgSP..PLF...LCLlwKMLLETDhinQIGYRVLERIgarALVAHVRTFADFL..VYEFstsaggqqlnkcieIL.ND..MVWKYNIVTLDR.LILCLAMRSH..........EGN.EAQVC.YF.IIQLLL.LKPND
  875- 1038 (226.37/115.80)	FRNRVSDFVKENSPEHWLQNDW.HTKHMNYHKKYPEKLY.FEGLAEQVD..PPVQIQ.SPylPIYfgnVCL..RFLPVFD...IVIHRFLELL...PVSKSLETLLDHLggLYKF................hDRPVTYLYNTLHYYERYLRNRDHLKRKLVHAIIGSlkDNRpQG.WClSDtYLKNVMNPREDN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      32.07|      10|      27|     114|     123|       3
---------------------------------------------------------------------------
  114-  123 (15.60/ 9.00)	RDLLKAILEK
  143-  152 (16.48/ 9.88)	REVIAYILER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      31|     318|     327|       4
---------------------------------------------------------------------------
  318-  327 (18.69/12.84)	IFFVLFQFAS
  351-  360 (19.45/13.72)	LMWVLLQFIS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01555 with Med23 domain of Kingdom Metazoa
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