<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01550

Description Mediator of RNA polymerase II transcription subunit 29
SequenceMAVPQQQASAASSAAGVSGPGWAGGPGPQQQQQLPAQLAGPAQNRFLQEQQQDFDPVQSYKMLIQQLKESLQTLMKVAAQNLIQNTNVDKRQKSSKVPIQRFDKCLQEFSVLCNHPGSLPEPGT
Length124
PositionTail
OrganismFukomys damarensis (Damaraland mole rat) (Cryptomys damarensis)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Hystricomorpha> Bathyergidae> Fukomys.
Aromaticity0.05
Grand average of hydropathy-0.607
Instability index67.21
Isoelectric point8.68
Molecular weight13440.03
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP01550
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.61|      18|      18|      15|      32|       1
---------------------------------------------------------------------------
   15-   32 (36.65/15.79)	AGVSGPGWAGGPGPQQQQ
   36-   53 (31.96/13.00)	AQLAGPAQNRFLQEQQQD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.37|      15|      18|      63|      80|       2
---------------------------------------------------------------------------
   63-   77 (23.83/10.48)	LIQQLK.ESLQTLMKV
   82-   97 (19.54/11.67)	LIQNTNvDKRQKSSKV
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP01550 with Med29 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MAVPQQQASAASSAAGVSGPGWAGGPGPQQQQQLPAQLAGPAQNRFLQEQQ
1
51

Molecular Recognition Features

MoRF SequenceStartStop
1) LMKVAAQNLI
2) SAAGVSGPGWAGGPGPQQQQQLPAQLAGPAQNRFLQEQQQDFDPVQSYKMLIQQLK
3) VDKRQKSSKVPIQRFDKCL
74
13
88
83
68
106