<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01544

Description Uncharacterized protein
SequenceMAQQRALPQSKETLLQSYNKRLKDDIKSIMDNFTEIIKTAKIEDETQVSRATQGEQDNYEMYVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAVDQRNQQLRALQEECDRKLITLRDEVSIDLYELEEEYYSSSEVSSWKQLLWAQLVLSADSVCQTGLISYSRKATCKARGSEAAGPPKKKRKKAQKKSREPGQKSAEHKAKFKGVKSPVASGSKNPAAVGEVEVSSPTRVSADGYATEPGSVFALEVLRQRLHEKIQQARGQDSTKELSTATLEKRRRRKQERERKKRKRKELLAKKKAAQAQEAEEMEPVAEATPGAACVEAPETALIFNKVEVSEEELASKAQRRKEKRQQVKGNLTPLTGRNYRQLLERLQVRRGRLEELREQDVGKAQQLEAKMKWTNLLYKAEGLRIRDNERQLEDALKRKEKRRAQRQRRWEKRSAQVVEKMQQRQDRRRQNLRKKKAARAERRLQKARKKGRVLPQDLERAGLV
Length497
PositionHead
OrganismFukomys damarensis (Damaraland mole rat) (Cryptomys damarensis)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Hystricomorpha> Bathyergidae> Fukomys.
Aromaticity0.04
Grand average of hydropathy-1.055
Instability index65.11
Isoelectric point10.02
Molecular weight57269.71
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01544
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     307.89|      97|      99|     206|     304|       1
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  170-  229 (47.98/16.25)	.....................................................ATCKA...RGSEAAG.PPKKKRK...............KAQ..KKSRepgqksaehkAKFKGVKSPVASGSKNPAAVGEVE
  230-  331 (149.29/71.10)	VSSPTRVSADGYATEPgsVFALEVLRQRLHEKIQQARGQ......DSTKELSTATLEK...RRRRKQE.RERKKRK...............RKELLAKKK.......aaqAQEAEEMEPVAEATPGAACVEAPE
  335-  405 (68.30/26.71)	IFNKVEVSEEELASKA..........QRRKEKRQQVKGNltpltgRNYRQL....LERlqvRRGRLEElREQDVGK...............AQQLEAKMK..................................
  410-  484 (42.31/13.45)	..................LYKAEGLRIR.................DNERQLEDA.LKR...KEKRRAQ.RQRRWEKrsaqvvekmqqrqdrRRQNLRKKKaaraerrlqkARKKG...................
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01544 with Med22 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ARGSEAAGPPKKKRKKAQKKSREPGQKSAEHKAKFKGVKSPVASGSKNPAAVGEVEVSSPTRVSADGYA
2) ERQLEDALKRKEKRRAQRQRRWEKRSAQVVEKMQQRQDRRRQNLRKKKAARAERRLQKARKKGRVLPQDL
3) HEKIQQARGQDSTKELSTATLEKRRRRKQERERKKRKRKELLAKKKAAQAQEAEEMEPVAEATPGA
174
422
259
242
491
324










Molecular Recognition Features






MoRF SequenceStartStop




1) GPPKKKRKKAQKKSREPGQKSAEHKAKFKGV
2) RKKRKRKELLAKK
181
291
211
303