<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01542

Description V-type proton ATPase subunit H
SequenceMGSVTSNLALLANNAALFLIASGVLWLVAAYCAFSVYIPLHIPSSYRCFCYTLGRPVMPVTLNMNMAMPSWFDIIGLSPDSQEDEPGIKRAAENVRALIEQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAGVTALSCWLPLRASFPQGPISGVNKDISILQCHGDCDPLVPLMFGSLTVEKLKSLVNPANVTFKSYQGMMHSSCQQAGALDLLKELKNIPMTLELLQSTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTDKDSEEKKKEPAITSQNSPEAREESSSSGNASSRKDDTNARDTYVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEDILLPIYQEIRNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKMTKMDIRGAVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISAEDCEFIQRFEMKRTPEEKQEMLQAEGSQCAKTFINLMTHISKEQTVQYILTMVDDMLQAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVAVETGTVSSSDSSQYVQCVAGCLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSDDPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWYAQLFTLTPTLTCGLSFAHPKSSY
Length944
PositionUnknown
OrganismFukomys damarensis (Damaraland mole rat) (Cryptomys damarensis)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Hystricomorpha> Bathyergidae> Fukomys.
Aromaticity0.07
Grand average of hydropathy-0.312
Instability index47.21
Isoelectric point6.59
Molecular weight106138.63
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell
vacuolar proton-transporting V-type ATPase, V1 domain	GO:0000221	IEA:InterPro

GO - Biological Function
hydrolase activity	GO:0016787	IEA:InterPro
nucleic acid binding	GO:0003676	IEA:InterPro
proton-transporting ATPase activity, rotational mechanism	GO:0046961	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
lipid metabolic process	GO:0006629	IEA:UniProtKB-KW
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01542
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     146.15|      47|      49|     362|     408|       1
---------------------------------------------------------------------------
  360-  406 (76.00/52.27)	GSQIEEDILLPI.YQEIRNTDMK..YKNRVRSRISNLKDAKNPNLRKNVL
  407-  456 (70.15/47.68)	CGNIPPDLFARMtAEEMASDELKemRKNLTKEAIREHQMAKTGGTQTDLF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.39|      40|     557|     210|     323|       7
---------------------------------------------------------------------------
   70-  111 (65.77/15.69)	SW...FDIIGLSPDSQE..DEPGIkrAAENVRALIEQEVKNGIPSNR
  263-  307 (59.62/151.89)	SWkklLDGPSTDKDSEEkkKEPAI..TSQNSPEAREESSSSGNASSR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.79|      15|     555|     309|     323|       9
---------------------------------------------------------------------------
  309-  323 (29.18/20.25)	DD.....TNARD..TYVSSFPR
  858-  879 (19.61/11.34)	DDpqvlaVAAHDvgEYVRHYPR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     118.61|      39|     485|     139|     185|      14
---------------------------------------------------------------------------
  139-  185 (55.84/54.79)	TALSCWlPLRAS...FPQGPISGVNKDiSILQCHGDCdplVPLMfgsLTV
  626-  667 (62.78/35.91)	TQLSSQ.KLRGSgvaVETGTVSSSDSS.QYVQCVAGC...LQLM...LRV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01542 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LDGPSTDKDSEEKKKEPAITSQNSPEAREESSSSGNASSRKDDTNARDTYVSSFPR
268
323










Molecular Recognition Features






MoRF SequenceStartStop




NANANA