Description | Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MAEEEDTNRVTSTWPDPPPFWKDFTPENISRYDTLKSDYATAHSTPDPDSITRLPSIPEDLINLQPPPEPTDGKWRLYSEAQALTDTLQSLTEAGVTPLLPASINPSSQDSKHLDRSFELKKLAKSILLNYLELVGVMSHNPAHGAAKIQDLKTLILNFHHTLNEYRPHQAREQLIQIMQDQLDTKRAETAAIRGVVDKARRMIEGLGSLELPRLDDEVVTTGSIGGRETEERRRVAAERCTVGSVELEFA |
Length | 251 |
Position | Middle |
Organism | Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383) (Pleurage anserina) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Sordariomycetidae> Sordariales> Chaetomiaceae> Podospora> Podospora anserina. |
Aromaticity | 0.05 |
Grand average of hydropathy | -0.592 |
Instability index | 49.65 |
Isoelectric point | 5.08 |
Molecular weight | 28131.24 |
Publications | PubMed=18460219 PubMed=24558260 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364060 ECO:0000256 ARBA:ARBA00003669 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP01510 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 3| 165.78| 37| 38| 66| 102| 1 --------------------------------------------------------------------------- 15- 49 (51.41/35.76) PDPPPF...WKDFTpENISRYDT..LKSdYATAHSTP.DPD 66- 102 (66.12/48.13) PPPEPTDGKWRLYS.EAQALTDT..LQS.LTEAGVTPLLPA 104- 143 (48.26/33.11) INPSSQDSKHLDRSfELKKLAKSilLNY.LELVGVMSHNPA --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 100.33| 31| 31| 172| 202| 2 --------------------------------------------------------------------------- 172- 202 (49.82/35.36) REQLIQIMQDQLDTKRAETAAIRGVVDKARR 204- 234 (50.51/35.94) IEGLGSLELPRLDDEVVTTGSIGGRETEERR --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) DGKWRLYSE 2) PFWKDFTPENISRYDTLKSDYATA | 72 19 | 80 42 |
© 2021 Shailesh Lab
Designed by Dr. Shailesh Lab & Dr. Jitendra K. Thakur Lab