<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01499

Description Mediator of RNA polymerase II transcription subunit 14
SequenceMAPVPLEGHQTPVTNNIPQEGNRGGSISLGMLIDFIIQRTYHELTVLAELLPRKTDMERKIEIYNFSARTRQLYVRLLALVKWANSASKVDKSAHIMAFLDKQSLLFVDTADMLARMARETLVHARLPNFHIPAAVEVLTTGTYSRLPACIRERIVPPDPITPAEKRSTLQRLNQVIQHRLVTGNLLPQMRNLKIEAGRVTFLVEQEFSVSLTVMGDGPTVPWRLLELEILVSDRETGDGKALVHPLQTRYVHQVVQSRLAESSNPLSEVYHILHYFCQSLQLEVLYSQTLRLIRDRLDDHIHVDEYTPGKCLSVSYWRELTNKDPRSELGYKLTVQVDQHDPARPLAIVHIPSLGSKESEIADRAIRSDQLSMECLLVHTIYVRTRSRLLDLKQELQTMLKDVECTLAGSPAILSVPILQPCLRAEHLLVTVDTHTGMLQCHVPQYEVPLIPELTTALNGDHSRLPTLISELRFWITQRRCEKTLQHLPATSHERLPVLLHPDHPISKISRHRMFIQLHRHPTVILIVAFKEKETSPCEIECSFYLAVVKHSSIEDDPHDDSIETEIPKMYLKVQSLIEFDTFVITHGPFTSVDNETPETNSLKRRSTGPSGRSDSSATLQNRRSKQPAYFIPELAHVVALCDERIPFVTLAQELTRRDIAHQGLQVEANATALVLKLVQLPAPSAGINTSCAWYALLKRLLSVSIRVQGKGMAKTWMAEFVFYGSPLSSSHPKEQGLRRPVYFQYEMGTADTISRTVDAILNDWAQIVHLYFIVHDLAEYFKMEKYNLRNMVTIKLYNYSKLVLTYGPNRGATVTVQWSTNDKAFKLIFGKSPTSTITNAHSIMKEQLEAHLNRHRNLAQLIHILHETLQPLTSISKLPIIPQLCVYNSRPQVPVQTFTIMPQCVTLVRIAYQGMYCLELRLRGSGLVSLRDGAYSRFDRSYVVDEFTPTQGLKAFLSKYVDESAVSRRRSQSEDDNPPSPVTMDSDGGSGSGNVGFLSHHRSGPQSPAQQRDGLRFHPPLTPPSGSNPHTPASPHTANISQTNQHQSFGSSPATSFNLASPPSLPPNTPNMLPHPSPGSGLVANSPLNPMHVPSPAGLMPTSSPGPCSNVQVGHSPAGSFMQTGHIDGSPFPSSQSMASPAASNWPGSPSVPRPSPARPTQSPGHALHSPQASDHKTGTHISRVLPQRSWAGAVPTLLTHEALELLCCPSPHPSGLPGPDLSPLERFLGCIYMRRQFQRFIQTDECLTAVNSTEPGVVHFKVESLQCRVGLNPQHLQSLHIKVQPLPDHKDQWTLEELQIIEKFFDTRAAIPPYKPNTLSGFGRMLNVPFNVLKDFVQIMKLELVPGLAQQQQLKWNVQWCLRIPPSGTPIVPTGMAAILVCRNKILFFLQITRIGLPYQGETPSLVLPLVYDVSTNLTQLAEKRDPSPASAMAAASLQLKRFAEYGANQSECSLFPAVRDLLANLTLPSDPPVMSQVPPAGGTPTQQIQSPAMQLHSPMAGNQGPPQAPYGIQGMPPMGIMGGPPQ
Length1530
PositionTail
OrganismApis mellifera (Honeybee)
KingdomMetazoa
Lineage
Aromaticity0.06
Grand average of hydropathy-0.239
Instability index59.75
Isoelectric point8.48
Molecular weight170039.33
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01499
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     421.08|      75|      76|    1022|    1096|       1
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  926- 1021 (67.21/27.50)	GSGLVslrdgAYSRFDRSYVVdE..FTPTQGlkaflskyvdesavsrrrsqSED.......DNPPS.P..VTmdsdggsgsGNV..GFL......SHHRSGPQ.SPA.....................Q.........QRDGLR....FHP....
 1022- 1080 (105.13/47.53)	......................P..LTPPSG....................SNP.......HTPAS.P..HT.........ANI..SQT......NQHQSFGS.SPAT.....SFNLAS.PP...SLPP.........NTPNML....PHPS..P
 1081- 1166 (107.09/48.57)	GSGLV.....ANSPLNPMHVPsPagLMPTSS....................PGPcsnvqvgHSPAG.SfmQT.........GHIdgSPF......PSSQSM.A.SPAA.....S.NWPG.SP...SVPR.........PSPAR.....PTQS..P
 1167- 1220 (60.37/23.89)	GHAL..............H...............................................sP..QA.........SD...HKT......GTHIS.RV.LPQR.....SWAGAV.PT...LLTH.........EALELLccpsPHPSglP
 1406- 1502 (81.28/34.93)	TPSLV.....L..PLVYDVST.N..LTQLAE....................KRD.......PSPAS.A..MA.........AAS..LQLkrfaeyGANQSECSlFPAVrdllaNLTLPSdPPvmsQVPPaggtptqqiQSPAMQ....LH.S..P
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     177.45|      54|      76|     387|     443|       2
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  387-  443 (87.51/54.65)	RSRLLDLKQELQTMLKDVEC..TLAGSPAI..LSVPILqpcLRAEHLLVTVDTHTGMLQCH
  463-  520 (89.95/48.23)	HSRLPTLISELRFWITQRRCekTLQHLPATshERLPVL...LHPDHPISKISRHRMFIQLH
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.78|      16|      18|     872|     888|       3
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  872-  888 (25.21/15.28)	QPLTSISKLPIIPQlCV
  892-  907 (31.57/15.59)	RPQVPVQTFTIMPQ.CV
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.71|      14|      23|     143|     156|       4
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  143-  156 (25.58/16.77)	TYSRLPACIRERIV
  169-  182 (24.13/15.35)	TLQRLNQVIQHRLV
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      79.88|      16|      22|     203|     218|       7
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  203-  218 (27.76/22.25)	LVEQEFSVSLTVMGDG
  225-  240 (26.51/20.84)	LLELEILVSDRETGDG
  698-  713 (25.61/19.83)	LLKRLLSVSIRVQGKG
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.01|      33|      52|    1314|    1347|       8
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 1314- 1347 (55.99/41.13)	IPPY.KPNTLSGFGRMLnVPFNVLKDFVQIMKLEL
 1367- 1400 (55.02/35.32)	IPPSgTPIVPTGMAAIL.VCRNKILFFLQITRIGL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01499 with Med14 domain of Kingdom Metazoa
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