<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01482

Description Mediator of RNA polymerase II transcription subunit 13
SequenceMTHPSHQTNGASLEDCHTNFFALTDLCGIKWKKLVWGEVAGDFGGTPLEDPVLSSFSRCLAGDILCVWRRVAATPATSGPATASATGAGIFDLGIAPSPAPPPLSLTAAKELWIFWYGEEPDLSGLVSPELIACESEQGSWESGLSYECRSLLFKALHNLIERCLLSRDFVRLGKWFVQPYDGFEKHRCSSSHLSFSFAFFVHGESTVCASVDVRQHPAVRHLTRTCLQRTQTSQSGVKVILAPYGLAGTLIGPVGRIDSQLLEEWKHFYPINSSNIEAGLPPLVEVLVGGVRMRYPSCYVLVTDMDDSPPDTPLSPPSSPASCEHPLLSQQELQAATELPERVWAECTLSSPISASKTESSTELGTWTFIDPTQKSSCICSKSATPGGWKSLASSQVQRDKGGRRVVPFHRRSTTQWDACPSVPANAPRSVLNRTEAPSTPPGGPPSYSRGPPTGGDCLPVPSVGSPGSPAPSPLPTPHSEPASVPPAEPTMPTLSPQPPPSHANTAPPLTPSQGPKSTSSACNNQVHSPVPGPTLKRPVLVSRECEEIYLENEQSLRCLYDYSIQEAWLNHPVKRFKESNNSPVNVRNNTLYPPMNSQIPQSQTPKIEIKQEPNVNVGDCIGRRTDPYEFDAAGEENGTSVDGLRRQRDDPSKPGSLFTSEGLQASYKDLDQIFDNSDPDTSSDETNLNQLQVQTPPESNRSGGLHEETRVDANNRHSNRGVGVLRPEELSKMFPTPPSLEHNPVASPCQLNDSLMDQTELSVPQRPLRHLPDIYPNMGSPQEEPIDDWSYVFKPAPICKMVGSSKYAPLTNLPSQSLPPVTLPSHCVYRPSWQCNPTSNNPDKPLPPTRPGSVQQQPCPPSPAPLGAPYRSATISGRPPPPPYDQPSPATSTTSSYLNKNLNSIEADTPGPTRAPESNSLIVNILLGDTVLNIFRDHNFDSCSLCVCNAGPKVVGNIKGADAGVYLTHSWSSGALFQDDDQIRCSCGFSAVVNRRLAHQAGLFYEDEMEITGIAEDPAEKKKASLVAVACGGGKPSEGLDVIPPSVLELLREQCLIIQSSASSLYRASRIYATMKSYPMLTPTINMLEFNDGNEVSLAALDQGKINGTHNERTNRIIGVHRWVFLRAKGPQCSGDIVRMMRALQPLLQDAVQKKCTTRMWEAPYTVAGPLTWRQFHRLAGRGTDDRCEPQPIPALVVGYDRDWLSLSPYALSYWEKLLLEPYAGPRDVAYVVVAPDSDCVVNKVKSFFRELSTTYEICRLGRHTPISKALRDGILRVGKSSVQKQIKQPIDDWFKLLGENQLGELLRLYAQVCNHRLAPYLTQVIQDRSLLDSGDSQSNKQQQQQQPQTTIPVTDTMPATPDVMSSKPESIEGENPRSETPSSNTTNTNSNTGNTTPTSQTATVHTNTTSGPDEEEVEPPAIVVYLVEPFSLGGPEDPDRRRLAILALLRAYSTAINSMPENIRSNINVQIISLESIMELGRARERRKIQDEMRALALNVFLQENSITATTSSNPTNTNSNTGNTTPTSQTATVHIITTSGPEDPDRRRLAILALLRAYSTAINSMPENIRSNINVQIISLESIMELGRARERRKIQDEMRALALNVFLQGRRLLNHNSTVKSLTGFGTAAAADLFLKSKDSYSNTLATIHQERNRAPYRLYSPAYVLAPLRAKSEAPESFGIAGPEECAVLYLSYCLSEDQSWLLAVATDDRGEIFETATINIDIPNRKRRKRASARRIGLQKLMDFILSVMSQGVQPWRLVVGRVGRIGHGELKGWSWLLSRKALLKASKHLKEICGQCSLLYPSAAPCVLSACLVSLEPDSTLRLMADQFTPDERFSQASVNCQLSTPQDVTCTHILVFPTSATTQSSQTAFQEQHINGPELGDDELFSALNDDMPEGMEGMGDFNDIFNVWPEAGAGGGQSPGGSPHRPEGSPMGGDGGGSGLGNHDGPGSPFPCSNTPRVAVAEQAEEVGTLLQQPLALGYLVSTAPTGRMPPWFWSACPHLEGVCPVFLKNALHLHSPAIQQNSDDLLQQQSALTAHPLDSQYTTDVLRYVLEGYNALSWLAVDANTKDRLSCLPVHVQALMQLYHAAAALV
Length2101
PositionMiddle
OrganismApis mellifera (Honeybee)
KingdomMetazoa
Lineage
Aromaticity0.06
Grand average of hydropathy-0.395
Instability index60.28
Isoelectric point5.75
Molecular weight229206.73
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01482
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     447.66|     103|     104|    1404|    1506|       1
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 1404- 1505 (186.70/84.24)	.....TATVHTNTTSGPDEEEVEPPAIVVYLVEPFSLGGPEDPDRRRLAILALLRAYSTAINSMPENIRSNINVQIISLESIMELGRA................................................RERRKIQDEMRALALNVFL
 1506- 1612 (195.08/88.34)	QensiTATTSSNPTNTNSNTGNTTPTSQTATVHIITTSGPEDPDRRRLAILALLRAYSTAINSMPENIRSNINVQIISLESIMELGRA................................................RERRKIQDEMRALALNVFL
 1641- 1745 (65.87/25.08)	K....SKDSYSNTLATIHQERNRAPYRLYSPAY................VLAPLRAKSEAPES.........................fgiagpeecavlylsyclsedqswllavatddrgeifetatinidipnRKRRK.....RASARRIGL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     259.97|      36|      40|     441|     478|       2
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  310-  334 (35.62/ 9.50)	..................PPDTP..LS..P.P....SSPASCEHPLLSQ........QEL
  441-  470 (52.66/18.33)	.................TPPGGPPSYSRGP.P....TGGDCLPVPSVGS........PGS
  508-  532 (32.61/ 7.94)	.................APPLTP...SQGPkS....TSSAC..NNQVHS........P.V
  821-  841 (32.00/ 7.62)	..................PPVTLPSHCVYR.P.....SWQC.......N........PTS
  842-  862 (36.31/10.27)	NNPDK.P..........LPPTRPGSVQ....................QQ........PCP
  863-  909 (39.27/15.87)	PSPAPlGapyrsatisgRPP..PPPYDQPS.PatstTSSYL..NKNLNS........IEA
 1929- 1963 (31.50/ 7.36)	...................PGGSPHRPEGS.P....MGGDG.GGSGLGNhdgpgspfPCS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.74|      29|     369|      31|      59|       4
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   31-   59 (54.80/37.50)	WKKLVWGEVAGDFGG...TPLEDPVLSSFSRC
  390-  421 (49.94/33.38)	WKSLASSQVQRDKGGrrvVPFHRRSTTQWDAC
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.58|      18|     369|      99|     126|       5
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   99-  126 (27.61/36.09)	PAPPPL........SLTAAkelwifwygeEPDLSGL
  471-  496 (29.97/13.95)	PAPSPLptphsepaSVPPA..........EPTMPTL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     255.75|      78|     395|     146|     230|       6
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  146-  230 (121.45/92.80)	SYECRSLLFKALHNLieRCLLsrDFVRLGKWFVQPYDGFEKHRCSSSHLSfSFAFFVHGESTVCAS....VDVRQHPAVRhlTRTCLQR
  544-  625 (134.30/80.29)	SRECEEIYLENEQSL..RCLY..DYSIQEAWLNHPVKRFKESNNSPVNVR.NNTLYPPMNSQIPQSqtpkIEIKQEPNVN..VGDCIGR
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.77|      25|     504|     785|     820|       8
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  726-  753 (41.11/22.32)	VLRPEELSKMFPtppSLEHNPVAS.PCQ.L
  794-  820 (37.66/20.19)	VFKPAPICKMVG...SSKYAPLTNlPSQsL
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---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.87|      25|     150|     934|     973|      10
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  944-  968 (46.95/49.32)	SCSL......CVCNAGPKVVGNIKGA.DAGVY
  975- 1006 (33.92/ 6.84)	SGALfqdddqIRCSCGFSAVVNRRLAhQAGLF
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01482 with Med13 domain of Kingdom Metazoa
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