<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01477

Description Mediator of RNA polymerase II transcription subunit 19
SequenceMMMGDQFRSKVEQYSPKSSPRGARSPVVSRQDSTGTLKTTISLGKNPSIVHSGPFYLMKEPPGESELTGATNLMNFYGLQHSYSKFSGKKLKEQLSSFLPNLPGIIDRPGHLDNSSLRSVIEKPPIGGKDLIPLTSVQLAGFRLHPGPLPEQYRYVNQAPQRKHKNKHKKHKHKPGEVPSGQEATTTDIGGSDTHEKKHKKQKRHDEEKEARKKRKKEKKRKKQKHSPEHSGGLTPSQHSNS
Length242
PositionHead
OrganismApis mellifera (Honeybee)
KingdomMetazoa
Lineage
Aromaticity0.05
Grand average of hydropathy-1.201
Instability index56.87
Isoelectric point10.10
Molecular weight27115.48
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01477
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      78.48|      14|      19|     195|     208|       1
---------------------------------------------------------------------------
  164-  177 (26.93/ 9.86)	HKNKHKKHKHKPGE
  195-  208 (27.70/10.30)	HEKKHKKQKRHDEE
  217-  229 (23.85/ 8.11)	KEKKRKKQK.HSPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.23|      22|      34|     102|     124|       3
---------------------------------------------------------------------------
  102-  124 (35.70/23.87)	LPGIIDRPGHLDNsSLRSVIEKP
  139-  160 (41.53/23.73)	LAGFRLHPGPLPE.QYRYVNQAP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01477 with Med19 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DQFRSKVEQYSPKSSPRGARSPVVSRQDSTGTLKTTISL
2) IPLTSVQLAGFRLHPGPLPEQYRYVNQAPQRKHKNKHKKHKHKPGEVPSGQEATTTDIGGSDTHEKKHKKQKRHDEEKEARKKRKKEKKRKKQKHSPEHSGGLTPSQHSNS
5
132
43
242










Molecular Recognition Features






MoRF SequenceStartStop




1) EKKHKKQKRHDEEKEARKKRKKEKKRKKQKHSPEH
2) QFRSKVEQY
3) YRYVNQ
196
6
153
230
14
158