<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01468
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MGEPQQVSALPPPPTQYIKEYTDENIRKGLAPKPPPPIRDHYMMFGNQFQCDDLIIRPLESQGIERLHPMQFDHKRELKKLNMSILVNFLDLLDILIKSPGSIKREEKLEDIKLLFVHMHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVVEMIQGCLASLPDDLPQSEGPDVACGGTKSSSAGPSFGCSSGQAPMLKSEPTDLEEAGSSCMAAGVLDKNTASLKREKTWDKDAAMCNIIDEIA |
Length | 254 |
Position | Middle |
Organism | Poecilia formosa (Amazon molly) (Limia formosa) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi>
Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata>
Ovalentaria> Atherinomorphae> Cyprinodontiformes> Poeciliidae> Poeciliinae>
Poecilia.
|
Aromaticity | 0.05 |
Grand average of hydropathy | -0.532 |
Instability index | 54.62 |
Isoelectric point | 5.80 |
Molecular weight | 28686.73 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 RuleBase:RU364060
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP01468
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 64.14| 18| 28| 177| 194| 2
---------------------------------------------------------------------------
177- 194 (32.32/22.23) QSEGPDVACGGTKSSSAG
208- 225 (31.82/21.78) KSEPTDLEEAGSSCMAAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 84.98| 24| 26| 23| 48| 3
---------------------------------------------------------------------------
23- 48 (41.55/33.11) DENIRKGLAPKPPPpiRDHYMMFGNQ
52- 75 (43.43/27.39) DDLIIRPLESQGIE..RLHPMQFDHK
---------------------------------------------------------------------------
|