<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01453

Description Mediator complex subunit 23
SequenceMMMRSSRPGRRHVGCRGDGGRGELLWKTEMIEEAFAGMFMDTPENERTKLISCLGAFRQYWGTLQQDSHEQCVQWIVRFIHSQHSPKRISFLYDCLAMAVETSLLPPRMVCVALISSESLEWERTRLWALTFKLIRKIIGGVDYKGVRDLLKAVLDKIQTIPITVSSAIVQQLLAAREVVEYILDRNACLLPAYFAVTEIRKLYPEGHLSHWLLGSLISDFVDSFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPTTLRFPLRGMLPYDKDLFEPQTGLLRYVLEQPYSREMVCNMLGLNKQTLNIAQQKQRCLVLEEQLVDLVVYAMERSETEEHFDADIGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDISKPQSTHSFAMTCIWIHLNRKAQNDNSKLQILIPHSLKLHHEFLQQSLRNKSLGMSDYKIALLCNAYSTNSDCFSLPMGVLVETIYGNGSMRINLPGTSCMASGSVTPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPNVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLNDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIHGTWCKDILQTIMSFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMANENDIITHFSMQGSPPLFLCLLWKMLLETDRINQIGFRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPSDFRNRVNDFVKENAPEHWLQSDWHNKHMNYHKKYPEKLYFEGLAEQVSPPLQLQSQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERHLRDRTNLKRKLVHAIMSSLKDNRTPGWCLSETYLKFGMNPREDNVWIPDDTYYCKLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLVITALPEPYWIVLHDRIISVLSSPALTSETEWAGDPFALLDFTACHQSYSEMNCSYVLALTHAVWHHSSIGQLSLIPKFLSETLKPIVQTELQLLYVYHLVGPFLQRFQQERTRCMLEIGVAFYEMLQAVDQHCQHLSYMDPICDFLYHIKYMYTGDSVKEQVEKIIMTLRPAMKLRLRFITHSSIIETSSSAAAAASSASASSSSAGTPQPPPSSLSSTNTAASPSSSSQHAHTPM
Length1409
PositionTail
OrganismPoecilia formosa (Amazon molly) (Limia formosa)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Ovalentaria> Atherinomorphae> Cyprinodontiformes> Poeciliidae> Poeciliinae> Poecilia.
Aromaticity0.09
Grand average of hydropathy-0.038
Instability index46.94
Isoelectric point7.96
Molecular weight160332.09
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01453
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.83|      17|      19|     257|     275|       2
---------------------------------------------------------------------------
  257-  275 (28.23/22.43)	DPTT..LRFPLRGmlPYDKDL
  277-  295 (27.59/14.95)	EPQTglLRYVLEQ..PYSREM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.99|      15|      19|    1052|    1069|       3
---------------------------------------------------------------------------
 1052- 1069 (23.98/21.73)	MSSLKDNrtpGWCLSETY
 1074- 1088 (30.01/17.34)	MNPREDN...VWIPDDTY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.77|      13|      18|     915|     927|       5
---------------------------------------------------------------------------
  915-  927 (22.72/12.55)	SDFRNRVNDFVKE
  936-  948 (27.05/16.23)	SDWHNKHMNYHKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.61|      15|      18|     429|     443|       7
---------------------------------------------------------------------------
  429-  443 (28.67/19.40)	CIPVPDISKPQSTHS
  448-  462 (28.94/19.67)	CIWIHLNRKAQNDNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.68|      12|      19|     502|     514|       8
---------------------------------------------------------------------------
  502-  514 (19.77/16.88)	YSTNSDCFSLPmG
  521-  532 (23.91/14.53)	YGNGSMRINLP.G
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.18|      13|      19|    1138|    1151|       9
---------------------------------------------------------------------------
 1138- 1151 (16.97/14.29)	VPGKDVgNALLNVV
 1158- 1170 (24.20/14.85)	VPRENI.TAWMNAI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.82|      12|      19|     372|     383|      10
---------------------------------------------------------------------------
  372-  383 (21.06/12.06)	HMVLSLHQKLAG
  392-  403 (22.76/13.64)	HLMWVLLQFISG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.69|      17|      79|     795|     813|      14
---------------------------------------------------------------------------
   76-   96 (26.00/ 9.21)	IVRFIHSQHSPKrisfLYDCL
  797-  813 (32.68/21.41)	IITHFSMQGSPP....LFLCL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.32|      13|      20|     589|     602|      16
---------------------------------------------------------------------------
  589-  602 (17.54/15.06)	SRLL..VYmEIESLGI
  607-  621 (19.78/10.94)	SQLLpnVF.KSHAWGI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.01|      17|      21|     729|     747|      19
---------------------------------------------------------------------------
  729-  747 (29.91/24.13)	HGTWC.KDILQTImsFTPHN
  751-  768 (28.10/15.54)	HTLSCfPAPLQAF..FKQNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.41|      20|     301|     868|     890|      24
---------------------------------------------------------------------------
  868-  890 (31.17/26.25)	IEILNDMVWkynIVTLDRLILCL
 1174- 1193 (37.24/22.14)	ITALPEPYW...IVLHDRIISVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.54|      17|     462|     655|     671|      25
---------------------------------------------------------------------------
  655-  671 (31.77/22.60)	PQTNQNQLHL.CVESTAL
 1119- 1136 (27.77/18.70)	PNPAAHALHVtCVELMAL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01453 with Med23 domain of Kingdom Metazoa
Unable to open file!