<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01440

Description Cyclin-dependent kinase 19
SequenceMDYDFKTKLAAERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRGMVKSLLYQILDGIHYLHTNWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDAYFLEEPLPTTDVFAGCQIPYPKREFLNEDEPEEKTDKNQTQQHQQTTGQTQGQTQQQAAAQQAPSQQNSAQTNGTTGTTGAAGGGGMQHVQDQGPPNKKPRIGPSGASSGTGVLQSEYQHSSSRLGYQSNVQGSTQSQSTMGYSSSSQQSSQYSHQTHRY
Length493
PositionKinase
OrganismPoecilia formosa (Amazon molly) (Limia formosa)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Ovalentaria> Atherinomorphae> Cyprinodontiformes> Poeciliidae> Poeciliinae> Poecilia.
Aromaticity0.09
Grand average of hydropathy-0.714
Instability index46.32
Isoelectric point8.66
Molecular weight56024.64
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01440
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.50|      25|      40|     102|     129|       1
---------------------------------------------------------------------------
  102-  129 (44.54/35.69)	HDLWhiiKFHRASK.ANKKPM.QLP.RGMVK
  143-  170 (34.96/20.17)	HTNW...VLHRDLKpANILVMgEGPeRGRVK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      94.03|      16|      41|     426|     441|       2
---------------------------------------------------------------------------
  394-  415 (19.09/ 7.34)	QQAPSQQNSaqtngtTGTTGAA
  426-  441 (27.35/13.34)	QGPPNKKPR......IGPSGAS
  452-  464 (20.54/ 8.39)	QHSS...SR......LGYQSNV
  465-  480 (27.05/13.12)	QGSTQSQST......MGYSSSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.10|      10|      23|     335|     344|       7
---------------------------------------------------------------------------
  335-  344 (19.67/11.87)	FL..EEPLPTTD
  358-  369 (14.43/ 6.99)	FLneDEPEEKTD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01440 with CDK8 domain of Kingdom Metazoa
Unable to open file!