<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01419

Description Mediator of RNA polymerase II transcription subunit 12 (Fragment)
SequenceMLVQDEAIVRLLCEWAVTTKRCGAHRALVVAKLLEKRQSELTTEKFGEADTADEKDSQDSTSVLPLGLPLYQNLLVNFLDTQAPVIDDRPSVDSKNAFANLVLLFAELIHYDVFSHDAYMCTLISRGSFTNAVGTQVGSATGCIPQSNKSISTPEPSLTGFMPDPSRGLSPGPGSAGCMGIGSMPGLGIPSMERQESLPMFEPPDNRPGSVKHEAPWESEMDLDDDRIDADLGKLLQHIKEGQQNMSDQPDSVGSDKDESTALNASTPLAHPPLVPCCTPGTENLANSANVNSSPPTTLSNTARHLLYTTHFPLPQDEAASHDCNQRHILLFGVGKVRDEARHTIKKMVKEIMKLFSKKTCMDIADSAKVKKNAKDGFNFEAVVSKFQSLSYFDQHVVTTICATSVIEMLSAFAMGNSNYLPLVEYIAFLFELMEIALNIHGLIEFTIQLLKELVDVEAQLAQKSSNLTGSYATSVGLSIVGVLYTYHCCLLVSQDQTLAVFDGLCRIIKHINTPTDCSSAERCILSYLFDMNSSCSYVK
Length540
PositionKinase
OrganismStegodyphus mimosarum
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Chelicerata> Arachnida> Araneae> Araneomorphae> Entelegynae> Eresoidea> Eresidae> Stegodyphus.
Aromaticity0.06
Grand average of hydropathy-0.111
Instability index40.95
Isoelectric point5.08
Molecular weight58943.49
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01419
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.39|      13|      15|     149|     162|       1
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  149-  162 (19.18/13.89)	KSIStPEPSLTGFM
  167-  179 (25.21/13.57)	RGLS.PGPGSAGCM
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01419 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ATGCIPQSNKSISTPEPSLTGFMPDPSRGLSPGPGSAGCMGIGSMPGLGIPSMERQESLPMFEPPDNRPGSVKHEAPWESEMDLDDDRIDADLGKLLQHIKEGQQNMSDQPDSVGSDKDESTALNASTPLAHPPLVPCCTPGTENLANSANVNSSPPTTLS
140
300










Molecular Recognition Features






MoRF SequenceStartStop




NANANA