<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01368

Description Mediator of RNA polymerase II transcription subunit 23 (Fragment)
SequenceKTEVIEEAFPGMFMDTPEDERTKLISCLGAFRQFWSSLSQESHEQCVQWIVRFIHSQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVVAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAMCNSWKLDPTTLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAHSDNSKLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGNMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSLALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTALSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPAPLQVFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIITHFSMQGSPPLFLCLLWKMLLDTDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMSYHKKYPEKLYFEGLAEQVNPPVQIQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERHLRERTNLKRKLVHAIIGSLKDNRPLGWCLSDTYLKCAMNAREENPWIPDDTYYCKLIGRLVDNILKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVINSPSLTSETEWVGYPFQLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLIPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNADRYSSHLNYLDPICDFLYHVKYMFTGDSVKDQVEKIICNLRPALKLRLRFITRTSKMEPAAVAQQPLNNGSPAQQPSQVPVNVALPVTQ
Length1356
PositionTail
OrganismAptenodytes forsteri (Emperor penguin)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Sphenisciformes> Spheniscidae> Aptenodytes.
Aromaticity0.10
Grand average of hydropathy-0.030
Instability index44.41
Isoelectric point7.86
Molecular weight155347.81
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01368
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.12|      20|     127|     571|     591|       1
---------------------------------------------------------------------------
  571-  591 (33.53/27.34)	FISQLLPTV..FKSHAWGIlHTL
  698-  719 (36.59/24.72)	WCKDILQTImsFTPHNWAS.HTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.68|      13|      17|    1025|    1040|       3
---------------------------------------------------------------------------
 1025- 1038 (24.26/23.15)	RPLG.WCLSDTYLkC
 1043- 1056 (24.42/10.01)	REENpWIPDDTYY.C
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.75|      12|     618|     683|     695|       5
---------------------------------------------------------------------------
  683-  695 (19.65/18.18)	HVTDFFTGsDSIQ
 1286- 1297 (24.10/16.58)	HVKYMFTG.DSVK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.94|      34|     618|     194|     235|       6
---------------------------------------------------------------------------
  194-  235 (45.93/53.74)	DF.VDTFRPTARINSIcGRCslLPVVNNsgaMCnsWKLDPTTL
  815-  849 (58.01/36.69)	DFlVYEFSTSAGGQQL.NKC..IEILND...MV..WKYNIVTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.20|      16|      19|     982|     997|       7
---------------------------------------------------------------------------
  982-  997 (31.52/24.61)	YKFHDRPVTYLYNTL.H
  999- 1015 (24.68/17.34)	YERHLRERTNLKRKLvH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      30|     326|     335|       9
---------------------------------------------------------------------------
  326-  335 (18.69/10.20)	IFFVLFQFAS
  359-  368 (19.45/10.93)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.01|      31|     783|     161|     191|      13
---------------------------------------------------------------------------
  161-  191 (57.48/29.16)	NACL..LPAY.FAVTEIRKLYPEGKLPHWLLGNL
  945-  978 (41.53/19.29)	NVCLrfLPVFdIVIHRFLELLPVSKSLETLLDHL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     199.57|      64|     860|     239|     305|      18
---------------------------------------------------------------------------
  239-  305 (108.21/79.95)	LKGLLPYDKDLfepQTALLRYVLE.QP.YSRDMVC...NMLGL..NKQHKQRCPVLEDQLVDLVVYAMERSETE
 1098- 1168 (91.35/58.96)	LMALAVPGKDV...GNALLNVVLKsQPlVPRENITawmNAIGLiiTALPEPYWIVLHDRIVSVINSPSLTSETE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.13|      16|     676|      26|      43|      19
---------------------------------------------------------------------------
   26-   43 (23.71/19.34)	SCLGA.....FRQfwSSLSQESH
  720-  740 (23.42/10.70)	SCFPAplqvfFKQ..NNVPQESR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      31.88|      10|      32|     122|     131|      22
---------------------------------------------------------------------------
  122-  131 (15.58/ 8.61)	RDLLKVILEK
  151-  160 (16.30/ 9.32)	REVVAYILER
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01368 with Med23 domain of Kingdom Metazoa
Unable to open file!