<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01328

Description AGAP005700-PA-like protein
SequenceMTYTFYLVLVKPSSVEEGQSPDGPSNVANAQASSSGAQPGNDPAATMPKMYLRVLSMIEFDTFVATHGPGTVIDDPIAGCSKRKLSAVESTSVACLGPAMKQQKTIYPAYFIPELAHVVAMCDEKLPFVALAKEFSHRRIPHGGLQVEANATSLVLKLLTLPQPKPPQIPPTPQQQGQQGGGQGQQQQQQQQPGPSNANADAKAAASNEPKTVHVPPLDKQVWNALLKRLLSVSVRAQVNKSNQTRLWTMELVFYGSPLPSLHHKEQGMRRAVYLQYEMLPVESVGKVVDQLLNDWSKIVYLYTLVHEFREQLQNEKYNLQNMVAIRSYNYTSLLLAYGPNKEVSVSICWDTDAKEFRLVFAGGNSAINAHSMMRDQLQAHLNHNYSLAQIVHILHETYQPLSSIAKLPIIPHLAILQSPKIPVLSFCIVPQSPNLLRISFQGVYCLEVRFRGGGLCTIRDGAYSRFDRSHVVEEFTPTQGLKGFLSKYVDETAVFRRRSQSEDDNPPSPVTMEDPSGHGGGGAGGGGGGGQGPGSVGSNTFLGGAAGMRGPQSPRDPGLRFAAPLTPPSGSNPHTPASPHPIGGGGGAGGAGGGGGGQGQGGQGGQQGHMNNFNMTSPPASHMPHPSPSGGLMPSSPLNAQPSPMAAHSPGPSNLPYMQNHTDGSPFAALSPAASNWPGSPGMPRPSPRPGQSPEHKVQTHYTSRVLPARSWAGAIPTLLTYEALDTLCRATSHPQKEVPGPELSPLERFLGSVFMRRQLQRIIHQEDSLMAMTSNEPGVVVFKADCLQYQVFLNPNHMQSLHLKVAQLPMGPMMDGKPPYQWAAEDLQILEQFFDQRVAAPPYRPAVMTSFTRMLILPAKVLMDFIQIMRLDLMPELGQGNKWNVQFVLRMPPSATPIVPVGTTTILSHRQKILFFIQITRVPYLPNMEWKDAVTMLLPMVYDMNMNHTTLAERREPMPPQLTSAVSAHLRRFSECTVLLPDECSLFPAVRDLLLTLTLPNEPPAPGQIQMQLGGVMQPGGGPGGPGGPMGGQIAGPTPQIAPQVGSSPGPMMHSPMQQQMQQPGGYGGMVGGAGGGPQAGGPGGGGPGGPN
Length1094
PositionTail
OrganismAnopheles sinensis (Mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.06
Grand average of hydropathy-0.305
Instability index61.70
Isoelectric point8.56
Molecular weight117481.05
Publications
PubMed=24438588

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01328
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     452.12|      61|      64|     520|     583|       1
---------------------------------------------------------------------------
  158-  195 (53.53/13.20)	...LLTLPQPK.PPQ..IPPTP.....QQ.QGQ.QG..GGQGQQ...QQ.QQQQPGP.........................
  503-  555 (93.67/34.00)	EDDN........PPS...PVTM.....EDPSGH.GG..GGAGGG...GG.GGQGPGSVGSNtflGGAAGMRGP......QSP
  556-  613 (99.24/32.16)	RDPGLRFAAPLTPPSGSNPHTP.....ASPHPIgGG..GGAGGA...GG.GGGGQGQ.GGQ...GGQQGHMNN.........
  614-  662 (64.31/18.05)	......FNM.TSPPASHMPH.........PSPS.GG..LMPSSP...LN.AQPSP..........MAAHSPGPsnlpymQNH
  993- 1044 (94.85/30.39)	RDLLLTLTLPNEPPA...PGQI.....QM.Q.L.GG..VMQPGG...GP.GGPG.GPMG.....GQIAG.PTP......QIA
 1045- 1092 (46.53/10.38)	PQVG.......SSP.GPMMHSPmqqqmQQPGGY.GGmvGGAGGGpqaGGpGGGGPGG.........................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     161.00|      48|      49|     829|     877|       2
---------------------------------------------------------------------------
  829-  877 (81.90/46.01)	LQILEQFFDQRVAA.PP.YRPAVMTSFTRMLILPAKVLMdFIQIMRLDLMP
  879-  928 (79.10/40.51)	LGQGNKWNVQFVLRmPPsATPIVPVGTTTILSHRQKILF.FIQITRVPYLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.97|      18|      19|     690|     708|       3
---------------------------------------------------------------------------
   38-   55 (33.00/15.98)	QPGNDPAATMPKMYL.RVL
  690-  708 (29.97/18.31)	RPGQSPEHKVQTHYTsRVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.65|      18|      19|     387|     404|       4
---------------------------------------------------------------------------
  387-  404 (31.30/19.08)	SLAQIVH..ILHETYQPLSS
  407-  426 (27.34/15.69)	KLPIIPHlaILQSPKIPVLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.45|      12|      41|     727|     742|       5
---------------------------------------------------------------------------
  727-  742 (19.33/20.41)	DTLCRATSHPqkevPG
  769-  780 (23.12/12.87)	DSLMAMTSNE....PG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.10|      24|      42|     259|     284|       7
---------------------------------------------------------------------------
  259-  284 (35.06/35.40)	LPSLHH..KEQgMRRAVY.LQyEMLPVES
  302-  328 (33.03/21.44)	LYTLVHefREQ.LQNEKYnLQ.NMVAIRS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.46|      10|      20|     654|     667|       8
---------------------------------------------------------------------------
  654-  667 (14.97/ 6.78)	SNLPYmqnhTDGSP
  676-  685 (23.49/11.89)	SNWPG....SPGMP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01328 with Med14 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FRRRSQSEDDNPPSPVTMEDPSGHGGGGAGGGGGGGQGPGSVGSNTFLGGAAGMRGPQSPRDPGLRFAAPLTPPSGSNPHTPASPHPIGGGGGAGGAGGGGGGQGQGGQGGQQGHMNNFNMTSPPASHMPHPSPSGGLMPSSPLNAQPSPMAAHSPGPSNLPYMQNHTDGSPFAALSPAASNWPGSPGMPRPSPRPGQSPEHKVQTHYTS
2) LTLPNEPPAPGQIQMQLGGVMQPGGGPGGPGGPMGGQIAGPTPQIAPQVGSSPGPMMHSPMQQQMQQPGGYGGMVGGAGGGPQAGGPGGGGPGGPN
3) TLPQPKPPQIPPTPQQQGQQGGGQGQQQQQQQQPGPSNANADAKAAASNEPKTVH
496
999
160
705
1094
214










Molecular Recognition Features






MoRF SequenceStartStop




NANANA