<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01327

Description AGAP008970-PA-like protein
SequenceMAQQAPEGLDVTELMFKLQSKVPIFKGNGNAKDNCNLLAAASVHGLVFVGTVGPELRVLRLKDITTGDRAVTDVVPLRTVPLPSEPFQLAVSCDHGFLAVDVVGNGGVPFIHIYSVPSFLTGSVVKLHEIRTSPQPGVRCSQICWNPVIHNMFSVRTETGGLSAYTLKEPTGLEFHSLDANAGAAQCACWSPKGKQLVVAFANGKLVQYKPDLKPARTIVCPPGVVEGGGGYDVLAVQWLSTYQFAAVFLPHAPDSVPALFIVNAPKVGNPVLINYDDVCYSQSGPRKGQVFLLHILPWNLLLMASANSMEVGILGTTETGEAPTWCQWTTTDEARAELPLTADKQESFPIGFALETGCTHELVIGEQAFPVMPMIHLLSTYGQLVSFNVLNKMPNVPNLCSPPKPAPDLTGGAFVMIDFEKSAPPQTTPSFQSNANTMTPQVGQQPQQPPPSSEISFAVPSGATSTPAVQKTKSFFNAGLASGDSAVPKSPLNLFGSVGSTKPPTVATTTTTIAPTFGKQITFGGSAGGAGGETKTSPFGGFGSTGGMGGFGSASMGTTPGGLPTMSAPPFQAAMASMAPPMASATPTFTSAGPADANKPLVTVPPTYVPPAPSQQQQSQAQPVAAPGQQTRTSRKSDVSSEDNNAIIRALTVDELKRFSRELVDMQQRNRSVSVQIGSKEESAGIIRNLRELEDIIAQANESTQSLVSDVQALRLGLNEAFAMVAEANSKSAIYNNPSLHQYQEEHVMSQASRRQLSALENMLQVNENQLRTVTKQLGAQWMAVEEAKRAQVRQRMHIPSLEVLYQTLSKQQEILNRQSEKLGYLKHRLGLKGTLKGLGDAEGRKATPLTHDDSGAIESLTDSILSMTLGDQVAADAKKLSEVKLAALRKALAGRKVVTVKPKRPDRVGLSSEVVRERRDEVRRLNLEQEKSQKAQAAKKEAEQKKQQQQQQQQQQQQAQKRPQQPQQPQQQSQQQQQPQQQSQQPVAKPLATSTASNKPFSFPAQAATGGSAGGMGSFSFGQTTITPMTADAASAPAKPIGGGGNISTGLSFGASNKENAEKKDSAAKENVAPKPPASGLFSFGSSTASTGSSPAAFKSPPETPSTAVTSGVGMTGKSVFSFAGTGANNQTPGLSFGSVSKPTFSFDPSAASTPSTLSFGSGSTGGATDAPLNLGKPKQTPATNENIPPVAVVDDETRKDKPLPPSFGPAVESNTTTKAPLPALTSLLQKVDPTAAAVAADGSQTKVASTSKGSAASTGLFGSSGGGSTFGEGGLFGSKSNTTASGDPVKSGGGFFSGLTFGGTTITPVVASSGTSTPTTASGGLLFGGVKPAPPTTKTDGTPPSGGFSFGSSFTATATVTPPSDQSKPEQKEETTVPAASSAVSSTTTPPKTVTVTSSGGFSFGSLPSLGKSLPSPAASVAPTASVASPTTPPPSTTTAAATTTTDPTAGLFGSISICSPTSTATTSPQTPPSSGGNIFSSSAFGAPKPAAGTSTASIFGGSATVGAGSSLFGAVSKPAAGFGVTTTTASTGGSGLFGSVVAPSTVSSTPVASSGGSLFGATSSTSTTTTTAGSIFGGGATSGGFFSSGTGGTATTTTSTGFGGGSIFGASATASPSTPASSGNIFGGSPATPSAGGGIFGTNNNNAASGGSIFGGSSAFGASSTPAGGGGNIFGSPAATSTQPSWTGGSGLFGSVGANTGSSGFASPQSPAAAPSQATQSIFGGGAAGGTAFGAASTPSNTVSAFGSPSGGGASAFSKPVSSAFGGTATFGSGTPTFGGAATFGGAPTFGGAPTFGSPKATFGGGAAFGVAPAATAIGSPTQSNNLFEQLGSSSTSVSFGGLAQQQATKPPQFGGSSFSSWRS
Length1868
PositionTail
OrganismAnopheles sinensis (Mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.06
Grand average of hydropathy-0.195
Instability index51.83
Isoelectric point9.01
Molecular weight188443.70
Publications
PubMed=24438588

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01327
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     104.79|      24|      24|    1769|    1792|       1
---------------------------------------------------------------------------
  551-  572 (31.10/ 6.61)	GfGSASMGTTP........GGLPTM.S.APPF
 1756- 1782 (33.10/ 7.68)	G.GASAF....skpvssaFGGTATFGSGTPTF
 1783- 1807 (40.59/11.73)	G.GAATFGGAP......tFGGAPTFGSPKATF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     126.07|      24|      25|     945|     968|       2
---------------------------------------------------------------------------
  616-  631 (20.73/ 7.46)	.QQQQSQAQ..P..VAAPGQQ...
  930-  953 (36.59/19.54)	EQEKSQKAQAAKKEAEQKKQQQQQ
  954-  977 (48.86/28.88)	QQQQQQQAQKRPQQPQQPQQQSQQ
  978-  991 (19.90/ 6.83)	QQQPQQQS....QQPVAK......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     132.26|      25|      25|    1559|    1583|       3
---------------------------------------------------------------------------
 1004- 1027 (33.01/ 7.89)	SFPAQAATG.GS.AGGM...GSF.SFGQTT
 1568- 1595 (37.99/10.52)	STSTTTTTA.GSIFGGGatsGGF.FSSGTG
 1596- 1616 (30.43/ 6.53)	GTATTTTST.G..FGGG......sIFGASA
 1714- 1741 (30.83/ 6.74)	SPAAAPSQAtQSIFGGG.aaGGT.AFGAAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     124.43|      26|      26|    1479|    1504|       5
---------------------------------------------------------------------------
 1279- 1304 (30.12/ 6.90)	FGSKSNTTASGDPVKS........GGGFF.SGLTF
 1489- 1516 (33.84/ 9.05)	GAPKPAAGTSTASIFG.gsatvgaG......SSLF
 1632- 1664 (30.55/ 7.15)	GSP..ATPSAGGGIFGtnnnnaasGGSIFgGSSAF
 1684- 1709 (29.92/ 6.79)	TSTQPSW.TGGSGLFG......svGANT..GSSGF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     141.50|      44|      46|    1380|    1425|       8
---------------------------------------------------------------------------
  437-  493 (38.93/ 6.12)	NTmtpqVG....QQPQQPPPSSEisfAVPSGATSTPAvqkTKSF.FnaG.LASGDSAVPkSPL
 1380- 1421 (53.38/15.46)	............VPAASSAVSST...TTPPKTVTVTS...SGGFsF..GsLPSLGKSLP.SPA
 1422- 1464 (49.19/ 9.64)	AS....VAptasVASPTTPPPST...TTAAATTTTDP...TAGL.F..G...SI..SIC.SP.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     120.91|      35|      46|     209|     254|       9
---------------------------------------------------------------------------
  215-  252 (59.11/51.79)	PARTIVCPPGVveGGG...GYDVLAVQWlSTYQFAAVFLPH
  258-  295 (61.80/26.16)	PALFIVNAPKV..GNPvliNYDDVCYSQ.SGPRKGQVFLLH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     248.41|      48|      48|    1157|    1204|      12
---------------------------------------------------------------------------
 1053- 1080 (37.19/ 9.37)	LSFGAS.NKENA...................................EKKDSAAKEN......VA....................................P.....K.........PPA
 1084- 1159 (42.75/12.06)	FSFGS..STASTGSSPAAF..........................KSPPETPST.......AVTSgvgmtgksvfsfagtgannqtpglsfgsvskptfsfDPSAAST.........PST
 1160- 1207 (78.76/29.53)	LSFGSG.STGGATDAPLNL..........................GKPKQTPATNENIPPVAVVD....................................DETRKDK.........PLP
 1208- 1261 (46.57/13.92)	PSFGPAvESNTTTKAPL..............................PALTSLLQKVDPTAAAVA....................................ADGSQTKvastskgsaAST
 1262- 1323 (43.14/12.25)	GLFGS..SGGGSTFGEGGLfgsksnttasgdpvksgggffsgltfGGTTITPV.......VA..S....................................SGT..ST.........PTT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.75|      12|      36|     641|     652|      14
---------------------------------------------------------------------------
  641-  652 (18.35/12.97)	SSEDNNAIIRAL
  680-  691 (18.40/13.03)	SKEESAGIIRNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.95|      36|      49|     745|     780|      15
---------------------------------------------------------------------------
  745-  780 (58.88/50.06)	QEEHVMSQASRR.QLSALENMLQVNENQLRTVTKQ...LG
  786-  825 (49.06/40.26)	VEEAKRAQVRQRmHIPSLEVLYQTLSKQQEILNRQsekLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.45|      21|      41|     109|     129|      16
---------------------------------------------------------------------------
  109-  129 (38.89/29.79)	PFIH.IYSVPSFLTG.SVVKLHE
  147-  169 (29.56/20.22)	PVIHnMFSVRTETGGlSAYTLKE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.30|      22|      41|     297|     322|      17
---------------------------------------------------------------------------
  297-  322 (33.32/30.67)	LPwnllLMA.SANSMEVGI.LGTTETGE
  339-  362 (32.97/18.64)	LP....LTAdKQESFPIGFaLETGCTHE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.66|      15|      21|     577|     595|      18
---------------------------------------------------------------------------
  585-  601 (23.16/14.12)	SATPTFTSagPADANKP
 1358- 1372 (27.50/ 6.83)	TATATVTP..PSDQSKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.79|      13|     113|    1551|    1564|      19
---------------------------------------------------------------------------
 1551- 1564 (23.04/12.21)	SSTPvASSGGSLFG
 1667- 1679 (28.75/12.17)	SSTP.AGGGGNIFG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.86|      12|      21|     403|     414|      21
---------------------------------------------------------------------------
  403-  414 (22.59/ 7.61)	PPKPAPDLTGGA
  425-  436 (24.27/ 8.80)	PPQTTPSFQSNA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01327 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DPTAAAVAADGSQTKVASTSKGSAASTGLFGSS
2) GGAFVMIDFEKSAPPQTTPSFQSNANTMTPQVGQQPQQPPPSSEISFAVPSGA
3) GRKVVTVKPKRPDRVGLSSEVVRERRDEVRRLNLEQEKSQKAQAAKKEAEQKKQQQQQQQQQQQQAQKRPQQPQQPQQQSQQQQQPQQQSQQPVAKPLATSTASNKPFSFPAQAATGGSAGGMGSFSFGQTTITPMTADAASAPAKPIGGGGNISTGLSFGASNKENAEKKDSAAKENVAPKPPASGLFSFGS
4) KSLPSPAASVAPTASVASPTTPPPSTTTAAATTTTD
5) QTPGLSFGSVSKPTFSFDPSAASTPSTLSFGSGSTGGATDAPLNLGKPKQTPATNENIPPVAVVDDETRKDKPLPPSFGPAVESNTTTKAPLPALTSL
6) TASGGLLFGGVKPAPPTTKTDGTPPSGGFSFGSSFTATATVTPPSDQSKPEQKEETTVPAASSAVSSTTTPPKTVTVTSSGG
7) VPKSPLNLFGSVGSTKPPTVATTTTTIAPTFGKQITFGGSAGGAGGETKTSPFGGFGSTGGMGGFGSASMGTTPGGLPTMSAPPFQAAMASMAPPMASATPTFTSAGPADANKPLVTVPPTYVPPAPSQQQQSQAQPVAAPGQQTRTSRKSDVSSEDNNAI
1235
412
896
1415
1133
1323
488
1267
464
1088
1450
1230
1404
648










Molecular Recognition Features






MoRF SequenceStartStop




1) AKKEAEQKK
2) QAQKRP
940
960
948
965