<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01320

Description AGAP012219-PA-like protein
SequenceMSASGGAVTGGSLPALLMANGGGGPPGLGGPGGGGGKGPGGPTGSKPDLKTGLGSSSGAGGGGSAGGSGSGSGGGAPGKVLLGGDKHETWQMELLMERLRTKAKSAQYKSFPEMSKSVRMSLLEKRYALDAVEKSNLQKTLDSMQYCIKVTTRQGLVERLDCLTRQLGLKLSEDTSGLFISSDMFYLEIILDPAGGTVQDVKVHHECKMKQQSCSELVACLQRGDFADFTTQLEGLASIYQLNAEKKIKVNAFVALQALETDLHTLYTLSAQRYPDVHSLLLKSPLGVVQKRRGGHPMRLTYFVAPYDLLDLDTRTMNVLSAELIAKERIGCSVAVVLEAASANKLQIQPLLVVNPSTGSSAATNTTPVYTPIEKHNSTSLPATFVLRLSKPMPINAAMMRTIRGIVAGGTGGGGPPVEGGATPGERVPSSLLALIAHHASGGFVTDLSRGLQVTLPDQYHCYYLTDNPALQGVMVSSIPFTEPQHVPKILTLLRQAAVFNQLLASCIRTTSANRSGMMGNGSLEPENGLSTVGSLVFEVTALSCQYITVSLMHPYEESLATVEFDLQNIANIAVRIYGCGDGGGGGEGEEQDGGEQETGERLSAVLQRCMSIPVTLRALMKHWEEQHEQKFKPKSVPGLTSSISSSASNGGGGGGGPSGSGGSGGSGLPNGEGGGAGTGEDGVGGANGFSLGSLGTGTTPLDGGGGGGTTNGGGGAANCQQQQQQQRALLLNGNNNNLTGGGNSLGLDFCDMLATGRNGTTVVGGAGMRTAVPPREPPEPLAGGMAKKRRMVDFCKSPKSDSDLSAAGNDGGAAEGADTGTPGSNSNSTATIGSSSDGHEGTGVPSSNRAEPFGAGGNEQTVGGTEGDTGGLDSKGNSLGVTTKDDTTTTSSTSSSASTHPAMTTTEANVRSAGALLLESLDFSALDDPNDELLGDPMAAVKAAVRPPTKRRRNSSSSSSSSSSSSSSSSSSSSSSGSEDVEETVDQVEAEMSSFFSETGNDHTPPPPPSAVVNDSAAKDTAPSLCITPQAAVGGELGSSGFGDKRPVVAPAPPTTTPSGGGLEIIPLATPTTSVVGAGGSLTSSVTITPIPTSTSTSTAQTSTSSSSSSKKSSSSSSHRKGADGERSSSGGSGKSSEKKKKRKADDAAMGPPNKLPYKTGGESSPSRSGIGGGSSSNKSSPKHSSPVHHSSPKGHHGGGGLGFHSPKHGTGATSSASPKHPLHSGGSSTGGGKPSMSALKSAAASGSSPGSKSSDGGGGASSSGGGGGSTGSSKEQRDKERSEKKALQFSSSSSSSGTGSPLGSSKMKNSNLKLKQLDLTSPGSSLTISMSPGELPSPASAPLIDLTGSPVMGSPLQSGGGIGSTSVSASNTASSMLQALQAAKFSRKPSAGGGPGGGASGSGGGGGVGAGSLSAVIDKLKSAQSVDDDGGAVLVLPEMTITQQSASTTTTASMGGMGASVNIGSFGALGGGGLKDSAKGGLLSATSLANCTSAGISSAGQLSSMSNSAPSLTAALTSGSKASEYMVKPSSDGIKLTIQNKKGSKGSGGGSKSSGGGSSSKSGLKPGVSSGPMSAKGLQQQQQQQQQANHTTSFSGAFPSSTKSPHYTSSTTGSSSSSKTPFQKSNSFGSLSGSGGAIGGMKAKVSSPKSTSNPGNSSSSYSSSSGAKEKGASGLSAGRSKSSSTASLAGSMLSAAASAAATTAGGTSSSTLVNPMSIMKMLGFPAGGLGNMEGFAKSLDTKFQIPKLSARTGGNTTGGGNTGGGSASASNLPGGDPGSSEGNKVASVRVDGGRKQKQMSSTPQQQLPVGPSALRQFTPSPSGGSNDGLASASNVSTRLLSDLLGAAAAAKNASKMGTGGGGAGNATSGTDGQSSLHPLLPNIVQKMLGSDGSLLSKSNSSDGSMFPGRASPGMMSSGGGGSRDGFRSAGGSAPGTPTTTSGPPMVLPPFPSPVSNDAGDLAGSTLMRPPSRPSSTISNHSHSSQDGMGDGAAAASGQPSPSMASMMMMNALAGGTGGQSPIQLDSTSTQQLMAALAAKSAGGGSGGGGGLLNHGSNHLNHHNHHNHLMAGGGGAGSGVPLKNHPSPASVSVHIVKSPAPSPLPFASPHSNSSSNHGGGVGGGSAVGAAGGPGVVGLDDDLLDEALIGISSK
Length2154
PositionMiddle
OrganismAnopheles sinensis (Mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.03
Grand average of hydropathy-0.360
Instability index53.97
Isoelectric point8.92
Molecular weight212202.08
Publications
PubMed=24438588

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01320
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.96|      20|      30|    1889|    1917|       3
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  651-  675 (18.66/11.15)	GGGGGgGPsGS.GGsG.GSGlPnG..EGG
 1762- 1785 (16.29/ 6.08)	GNTGG.GS.ASaSN.LpGGD.P.GssEGN
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|    1437.34|     523|     649|     831|    1478|       4
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  691- 1011 (313.37/49.38)	........................................................................................................................................................................................................................................................................................................................................................................................................................SLGSL.......GTGTT....PLDGGGGGGTTNGGGGAANCQQQQQQQRALLlngNNNNLTGGGNSLGldfcdmlATGRNG....................TTVVGGAGMRTAVPPreppeplaggmakkrrmvdfCK...SPKSDSDlsaagnD...GGAAEGADTGTPGSNSNST...................................ATIGSSSDGHEGTGVPSS........NRAEPFGAGGNEQTVGGTEGDTGGLD...SKG....NSLGVTTKDDTTTTSST.......SSSASTHPAMTTTEANVRSAGAlLLESLDFSALDDPndellGDPMAAVKAAVrpptkrrrnsSSSSSSSSSSSSSSSSSSSSSGSEDVEETVDQVEAEMSSFFSETGNDHTPPPPPS
 1012- 1478 (462.01/95.35)	AvvndSAAKDTAPSLCITPQAAV......GGELGS.SGFGDKRPVVAPAPPTTTPSGGGLEIIPLATPT...........................TSVVGAGGSLTSSVT.ITP...IPTSTStSTAQTSTSSSSSSK...KSSSSSSHR.......KGADGERSSSGGSGKSSekkkkrkADDAAMGppnklpykTGGESS.....PS..RSGIGG.GSSSNKSS.......PKHSSPVHHSSpkghhGGGglGfhspkhgtgatssaspkhplhsggsstgggkpSmsalksaaasgsspgskssdggggasssgggggstgsskeqRDKERSekkALQFSSSSSSSGTGSPLG....SSKMKNSNLKLKQLDLTSPGS..SLTIS.........MSPG......ELPSPASAPLIdLTGSPvMGSPLQSGGGIGSTSVSASNTASSMLQALQAAKF...SRKPSAGGGPGGG.......ASGSGG....................GGGVGAGSLSAVIDK....................LK...SAQSVDD......D...GGAVLVLPEMTITQQSASTTTTASMGGMGAsvniGS.FGALGGG...GLKD..............................................................................................................................................................................................................
 1482- 1702 (269.78/36.55)	........................................................GGLLSATSLANCT...........................SAGISSAGQL.SSMSnSAP......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................sltAALTSGSKASEYMVKPSSdgikltiqNKKGSKGSGGGSKSSGGGSSSKSGLKpgvSSGpmsaKGLQQQQQQQQQANHTTsfsgafpSSTKSPHYTSSTTGSSSSSKTP.FQKSNSFGSLSGS.....GGAIGGMKAKV..........SSPKSTSNPGNSSSSYSSSSGAKEKGASGLSAGRSKSSSTASLAGSMLSAAASAA
 1703- 2141 (392.18/56.68)	A....TTAGGTSSSTLVNPMSIMkmlgfpAGGLGNmEGFAKSLDTKFQIPKLSARTGGN.......TTGggntgggsasasnlpggdpgssegnkvASVRVDGGRKQKQMS.STPqqqLPVGPS.ALRQFTPSPSGGSNdglASASNVSTRllsdllgAAAAAKNASKMGTGGGG.......AGNATSG........TDGQSSlhpllPNivQKMLGSdGSLLSKSNssdgsmfPGRASPGMMSS.....GGG..G................................S.........................................RDGFRS...AGGSAPGTPTTTSGPPMVlppfPSPVSNDAGDLAGSTLMRPPSrpSSTISnhshssqdgMGDGaaaasgQ.PSPSMASMM.......MMNALAGGTG.GQSPIQLDSTSTQQLMAALAAK........SAGGGSGGG...........GGllnhgsnhlnhhnhhnhlmaGGG.GAGS...GV.P....................LKnhpSPASVSV......HivkSPAPSPLP...FASPH.SNSSSNHGGGVGG....GSaVGAAGGPgvvGLDD..............................................................................................................................................................................................................
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.23|      17|      17|     126|     142|       7
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  126-  142 (26.52/20.63)	RYALDAVEKSNLQKTLD
  145-  161 (28.71/23.04)	QYCIKVTTRQGLVERLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      28.63|       9|      17|     444|     453|       9
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  444-  453 (11.83/ 9.78)	FVTDlSRGLQ
  464-  472 (16.79/ 8.82)	YLTD.NPALQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.53|      11|      24|     236|     246|      10
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  236-  246 (16.83/ 9.07)	LASIYQLNAEK
  263-  273 (17.70/ 9.92)	LHTLYTLSAQR
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---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.37|      13|      28|     524|     539|      11
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  524-  539 (18.44/19.82)	LEP.ENGLSTVGslvFE
  553-  566 (19.93/11.23)	MHPyEESLATVE...FD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.20|      24|      27|     312|     335|      13
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  312-  335 (38.89/29.00)	LDTRTMNVLSAE..LIAKERIGCSVA
  338-  363 (31.31/21.41)	LEAASANKLQIQplLVVNPSTGSSAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.69|      29|     509|      69|      98|      16
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   69-   98 (48.46/28.72)	GSGSGGGApGKVLLGGDKHETWQMELLMER
  581-  609 (51.23/25.95)	GDGGGGGE.GEEQDGGEQETGERLSAVLQR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01320 with Med1 domain of Kingdom Metazoa
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