<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01261
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MEETLDDLFGDSGGLDLSLSAPVPPKALPARIDELRILGCCQKIAWSRTGAIAYIAPDGSKAFLRNLNCSPEDGKWSLSDGDHEHPITEAQTGHTLVHLAWNEPGTDLAVVDSCGRISIVGMSIGLNVLIQSRPPALDPDDDGNQPVGLMWLALNRSVHTFSHAGRASGRWAYVRYPRRPMGPFHPLHKLALFVVTRSGKLKLLYQNQESKWGDMVIELQNTGYTDDVLTHASMTPVDGKIYAR |
Length | 244 |
Position | Tail |
Organism | Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete's foot fungus) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Eurotiomycetidae> Onygenales> Arthrodermataceae> Trichophyton.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.248 |
Instability index | 42.67 |
Isoelectric point | 5.96 |
Molecular weight | 26734.09 |
Publications | PubMed=22951933
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP01261
No repeats found
|