<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01257
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MIVTYSASNELRLYRAMLKWEGTPVDSNTQRPNNSIAVPSVQLAHIEVEVPAVVPSPSTYVIGNEDNITNNANGLFALTHLQVVACPVDAPGGQTAPMILAVFSCLLHNIHGRSHLQHPSVIARWELRSVNQNLHKSFDDIVSKKPRNPLLPSTELNRQADTYFDRHIVSIDYMETGNIFAITTDDGNIAFYDAKAFTPLSGVEDIETVTSLPQSGFTFPAAISPSVHISFSPSGCIAASLDEKSHVQMRVMEHSFGLEQDGLFNDGKFMSALAALTMAYCRACSSDSNNDDILMIVIQQLNQDSHKKFIDEVYRALSMNVTVEQDKLMNNPYILKCFSMQAALGFKNRLERRNLAAAVPWLTLQLRQISILLTYILHFNKAGADVECYDPETLRITLGNVKWALDLAKYIVDDLFEISDNLNSQSSSQDSGSSSGKLYESLSTILIISSIPRSFLRYICRGLRGLTNGFRNAMNLSNESYQIYSQIVTVITESALKVDVYEKLLATVESDVKHAYQNAGFNNADRAAPERDLLINGSIPPVLQPAVTAILTKTVPMIRNEANPMYLFLQDYSWLGVGDDKRADLFRHKYEIDILRKVLIPLDESRGAVRPSRRCVRCCAISEEIPPKSMAAVKMLMRTAVLRACTCGGMWSMSNASNLRGSTTLPGWRQPG |
Length | 672 |
Position | Tail |
Organism | Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete's foot fungus) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Eurotiomycetidae> Onygenales> Arthrodermataceae> Trichophyton.
|
Aromaticity | 0.08 |
Grand average of hydropathy | -0.101 |
Instability index | 54.42 |
Isoelectric point | 6.23 |
Molecular weight | 74587.45 |
Publications | PubMed=22951933
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP01257
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 56.44| 16| 167| 127| 142| 2
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127- 142 (28.01/19.60) LRSVNQNLHKSFDDIV
298- 313 (28.43/20.00) IQQLNQDSHKKFIDEV
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 128.46| 39| 43| 212| 251| 4
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212- 251 (64.51/40.55) LPQSGFtFPAAISPSVHISFSPSGCIAASLD.EKSHVQMRV
258- 297 (63.95/36.13) LEQDGL.FNDGKFMSALAALTMAYCRACSSDsNNDDILMIV
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