<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01096

Description Mediator of RNA polymerase II transcription
SequenceMVSISIVFANTQHMTGIDDMVRAVLTCKEIQGRCWTDVVRDLLHGAFLLIHDNTSILPPSVANSFLYLRLPRVLQKLCRTETPHESLIGGLKALAGVRSLLNASDLKARCNTLQFFVNVLGDLDMVNDQEKAAIMQIRFEGQAGVMEHYSADSQPPINLVLKAEPTLLSILKVLNEENLQMPERLSQMLNPLMSGKGLLYIVAAASATDQMGLFAGKLIRINEHYRAASLSDNGGGEIFDLSFLLLHRLSQYHSTKFWLPPGDPFFQSWYFKTANQLVRNIHTREDVDTLARLREFDLMEVEEAFARLRRGHTGWVMVRTWDFVLCQVAPIGECIVDQVKKNTITTEELKHVFTGLLRVKVNGVQCMCSPLLCLAQYLALRGDDIARMVAEKLSTFLDSATSVEMDRSKHVTDRISFMINSARRFLMSFVASEERPLPPFNWFGIGRMLARQFPTVSEDHFPLLSKPENIPYLLANSLRVGCVASALVSRIIVCTELAQFDVWISSLVDAVHRLNTPWGIKTWCDISIALCFVDPSECAPRLIAYLDSSFPITHRDLFCVAPRGGPLASFLVQLFLVALRYTSPPSPSTAATICRDVQKNSNDLSVRYDATLVSLRQFSTIGHLYESFDVCRGGALYPSVNFVGIFLTQLAWHSSSEAKVMKNELPEDLVLSVLWADPHLLKPETIVALYNPQEAKQRHKIMQLFCVLRKVGIF
Length714
PositionTail
OrganismTrichuris trichiura (Whipworm) (Trichocephalus trichiurus)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichuridae> Trichuris.
Aromaticity0.09
Grand average of hydropathy0.121
Instability index36.24
Isoelectric point7.02
Molecular weight80209.32
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01096
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     183.69|      41|     201|     293|     334|       1
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  293-  334 (71.22/43.15)	LREFDLMEVEEAFARLRRGHTGWvMVRTW...DFVLCQVAPIGEC
  451-  482 (47.82/24.38)	.RQFPTVS.EDHFPLLSKPENIP..........YLLANSLRVG.C
  497-  538 (64.66/35.16)	LAQFDVW.ISSLVDAVHRLNTPW.GIKTWcdiSIALCFVDP.SEC
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     171.83|      53|     146|     390|     447|       3
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  390-  447 (84.08/63.28)	AEKLSTFLDSATSVEMDRSKHVTDR....ISFMInsaRRFLMSFVASeeRPLPPFNWFGIGR
  539-  595 (87.75/53.23)	APRLIAYLDSSFPITHRDLFCVAPRggplASFLV...QLFLVALRYT..SPPSPSTAATICR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     205.13|      71|     498|     102|     191|       4
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  102-  191 (107.31/113.24)	NASDLKARCN.TL....QFfvNVLGDLDMVNDQEKAAIM..QIRFEG............QAGVMEhysadSQPPINLVLK...AEPTLLsilkvlneenlqMPERLSQMLNP
  600-  692 (97.81/65.91)	NSNDLSVRYDaTLvslrQF..STIGHLYESFDVCRGGALypSVNFVGifltqlawhsssEAKVMK.....NELPEDLVLSvlwADPHLL............KPETIVALYNP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01096 with Med24 domain of Kingdom Metazoa
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