Description | Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MAEQAQARMLSAAFPTPPPYYKHFTKQNVTKVRQIRKEAATNSDQVDVGSLPADLRYLIPPEPPADGRYKSFGAQHDLAQPAQSLAQAGIQELFPADAAHLDPTPHLQTLTRAVLLNFLELVGTLSVNPTQGPEKVEHLQTLFYNLHDLINRYRPHQARESLIMTMEDQLDKIKAQVKSVNSAKDRMEQVLSDIRVQATSETANTPAKQEKPLASETAQPTDTIQKAMYDALEFDLDD |
Length | 238 |
Position | Middle |
Organism | Aureobasidium pullulans EXF-150 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes> Dothideomycetidae> Dothideales> Saccotheciaceae> Aureobasidium. |
Aromaticity | 0.06 |
Grand average of hydropathy | -0.560 |
Instability index | 30.91 |
Isoelectric point | 5.51 |
Molecular weight | 26554.64 |
Publications | PubMed=24984952 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364060 ECO:0000256 ARBA:ARBA00003669 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP01078 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 48.98| 15| 23| 74| 88| 1 --------------------------------------------------------------------------- 74- 88 (25.84/11.48) AQH.DLAQPAQSLAQA 98- 113 (23.14/ 9.68) AAHlDPTPHLQTLTRA --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) LEFDLD 2) LPADLRYLIP 3) PYYKHFTKQN | 232 51 19 | 237 60 28 |
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