<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01027

Description Pre-mRNA-processing 40A-like protein
SequenceMSNNNPQYPGLQPIRPPIPGSMDPQRNFGQLMPVQFRPVVPAPPPPQQQQFVPMPAQHYHQQFNVGMPPQNQQPQFSQPIQQFQPRVGQQLPLPSQMIPMPVPRPNMQTSSESMMPQPDSQAPNGYTPGLGGPGMSISSSFMFASSSYGQAPQNNFNSTGQYQPVPQIQPPTGSSSQSITPGTAPQSNGEQPTVTTVMPSATIIQPHLAKGSSSDWIEHTSATGRRFYYNKRTKLSSWEKPFELMTPIERVDASTNWKEYTSPDGRKYYYNKITKESKWLIPEELKFAREQVGKAMVNGTLPEPLLTPCTQPSANSVTEAMPSADNSSVPAQGEQTSPISVAPVVTTSPSNLQSEITSGSRDSPTAITITGTEVDEPEVPVNIITPSDSSLGSDKAFVSDINTAATPMNDVSNVSAQDTVGSADGVLGEDKEDGKIDSIGENVNDVASETKSVEPESFVYANKMEAKDAFKALLESVNVGSDWNWERAMRLIINDKRYGALKSLGERKQAFNEYLSQRKKQEAEEKRMKHKKAREDFRKMLEESTELTSSIRYSKAIAIFENDDRFKAVERERDRKDMIESFLEELLNKERAKVLEERKRNTVEYRKFLESCDFIKANTQYRKVQDRLEADERCSQLEKIDRLEIFQDYLRDLEKEEEEQKKIQKEELRKTERKNRDEFRKLMDEHSTSGILTAKTHWRDYHSQVKDLPAYLAVASNTSGSTPKELFEDVVEELEKQYQEEKSQIKDAVKSAKITLSSTWTFEDFKSALSEHISSPPISDSNLKLVFDEVLERAREKEEKEAKKRKRLADAFFHLLYSTKDITESSKWEDFRQLLEDSQEFRSVGDVSLSKQMFEVYVAQLKEEAKENERKRKEERAKKEKDREERERRKSKQRREKEGGRERWKEETHKRDRTDSDSVDLNEVHISKENKRKQHQSPDHVSLETDKERTKKSHGHSSDRKKSRRHGSGHESDEGRHKRHRRDHRDSHREGGQLEDGEFGNDVVMDRW
Length1008
PositionUnknown
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.07
Grand average of hydropathy-1.076
Instability index60.12
Isoelectric point6.16
Molecular weight115317.94
Publications
PubMed=22089132
PubMed=24767513
PubMed=30397259

Function

Annotated function 
GO - Cellular Component
U1 snRNP	GO:0005685	IBA:GO_Central
U2-type prespliceosome	GO:0071004	IBA:GO_Central

GO - Biological Function
RNA binding	GO:0003723	IBA:GO_Central

GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro
mRNA splicing, via spliceosome	GO:0000398	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01027
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     112.11|      28|      38|     213|     250|       1
---------------------------------------------------------------------------
  213-  240 (54.98/25.02)	SSDWIEHTSATGRRFYYNKRTKLSSWEK
  254-  281 (57.13/41.88)	STNWKEYTSPDGRKYYYNKITKESKWLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     394.32|      65|      65|     742|     806|       2
---------------------------------------------------------------------------
  463-  532 (70.54/35.31)	KMEAKDA....FK.AllES.VNVGSDWN.....WErA...MRLI...INDKRY.GALKSLGER.KQAFN....E...YLsqR............KKQEAE....EKRMKHKK
  534-  599 (57.24/27.37)	REDFRKM....LEeS..TE.LTSSIRYSkaiaiFE.NddrFKAV...ERERDR.KDMI.ESFL.....E....E...LL..N............KERAKV....LEE...RK
  600-  664 (48.84/22.35)	....RNT....VE.Y..RK.FLESC...........D...FIKA...NTQY....RKVQD....RLEAD....ErcsQL..EkidrleifqdylRDLEKE....EEEQKKIQ
  680-  740 (57.94/27.79)	RKLMDEH....ST.S..GI.LTAKTHW.......R.D...YHSQvkdLPAYLAvASNTSGSTP.KELFE....D...VV..E............EL.EKQ....YQE.....
  742-  806 (101.07/53.54)	KSQIKDA....VK.S..AK.ITLSSTWT.....FE.D...FKSA...LSEHIS.SPPISDSNL.KLVFD....E...VL..E............RAREKE....EKEAKKRK
  807-  881 (58.68/28.23)	..RLADAffhlLY.S..TKdITESSKW.......E.D...FRQL...LEDSQE.FRSVGDVSLsKQMFEvyvaQ...LK..E............EAKENErkrkEERAKKEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     159.66|      25|      28|     105|     129|       3
---------------------------------------------------------------------------
   22-   45 (23.46/ 7.79)	MDPQRNFGQLMPvqfRPV.VPAP.....PP.
   46-   66 (35.18/15.29)	PQQQ....QFVP...MPA.QHYH.QQF.NVG
  105-  129 (48.21/23.62)	PNMQTSSESMMP...QPD.SQAP.NGY.TPG
  133-  160 (22.87/ 7.42)	PGMSISSSFMFA...SSSyGQAPqNNFnSTG
  170-  192 (29.94/11.94)	PPTGSSSQSITP...GTA.PQS..NGE.QP.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     117.19|      35|      74|     882|     916|       4
---------------------------------------------------------------------------
  882-  906 (35.22/15.82)	..................DREERERRKSKQRRE..K...EGGR............ERWKE
  907-  952 (46.25/23.17)	ETHKRDRTDSdsvdlnevHISKENKRKQHQSPD..HvslETDK............ERTKK
  954- 1008 (35.72/16.16)	HGHSSDRKKSrrhgsgheSDEGRHKRHRRDHRDshR...EGGQledgefgndvvmDRW..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     133.83|      34|      34|     378|     411|       5
---------------------------------------------------------------------------
  344-  372 (31.83/15.09)	......VVTTSPSNLQSEITSGSrDSPTAIT.ITGT
  378-  411 (57.20/32.46)	EVPV.NIITPSDSSLGSDKAFVS.DINTAATPMNDV
  413-  446 (44.81/23.98)	NVSAqDTVGSADGVLGEDKE.DG.KIDSIGENVNDV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.59|      15|      95|     194|     208|       8
---------------------------------------------------------------------------
  194-  208 (27.90/20.68)	VTTVMPSATIIQPHL
  292-  306 (25.69/18.38)	VGKAMVNGTLPEPLL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01027 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AKENERKRKEERAKKEKDREERERRKSKQRREKEGGRERWKEETHKRDRTDSDSVDLNEVHISKENKRKQHQSPDHVSLETDKERTKKSHGHSSDRKKSRRHGSGHESDEGRHKRHRRDHRDSHREGGQLEDGEFGNDVVMDR
2) DKAFVSDINTAATPMNDVSNVSAQDTVGSADGVLGEDKEDGKIDSIGENVNDVAS
3) MSNNNPQYPGLQPIRPPIPGSMDPQRNFGQLMPVQFRPVVPAPPPPQQQQFVPMPAQHYHQQFNVGMPPQNQQPQFSQPIQQFQPRVGQQLPLPSQMIPMPVPRPNMQTSSESMMPQPDSQAPNGYTPGLGGPGMSISS
4) MVNGTLPEPLLTPCTQPSANSVTEAMPSADNSSVPAQGEQTSPISVAPVVTTSPSNLQSEITSGSRDSPTAITITGTEVDEPEVPVNIITPSD
5) SSYGQAPQNNFNSTGQYQPVPQIQPPTGSSSQSITPGTAPQSNGEQPTVTTVMPSATIIQ
865
394
1
296
146
1007
448
139
388
205










Molecular Recognition Features






MoRF SequenceStartStop




NANANA