<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01026

Description Tyrosine kinase family protein
SequenceMGSIQEAVSITEERVKGVEENDTVYVAVGLNAEKNKKLLHWTTHKFSGNSICLLHIHQPDLVNSFSKAETNVFEYEPKDHATKAFQEHGSQTVHELLDKYILTLVPAGASKLLIEKDDIEKGIIEAIAQHNIRCLVMGAAADRHKMGVDSENTPGIVTAPVVLMLDSNTEAKQSEKIKSELIPDVLKYLDSSDMEETENGNSRCSLNAEWSFNSVIARTKLTDLLVHEDDEELQNWRAKEISCRKEVEVQLAREKQDVQEMKNQRDKIICELQMVQDQSSTLRNQMLESKCMVTELEEKIISAVDLLISFKEKRDKLRIEHANAVRKVEVLRKFGEVDTTSSYVVEFPAFSFMEINEATQDFDQSWKIGEGRYGSVYKGLLRNMPVAIKMLPSYGCQNQLEFQHQVEVLSRVRHPNLLTLIGSCAESKSLVYEYLNNGSLESHLACKDRTPLPWQIRISIATDICSALIFLQSSKPCIIHGNLKPSKVLLDANFVAKLGDLGIPSLVQHSMDSADTGTVVCNNSHKHLAYVDPECLVTGKFTPESDVYSFGIILLQLLTGRPLSGLVRDMKCALEMENLKTVLDFSAGEWPLHQTTQLAYLALRCCEKTWLNRPDLVSEIWSVLKPFRTICIDRRQELTSKKLQRAPSHFVCPIVQEVMEDPYIAADGFTYEEEAIRGWLDSGHNTSPMTNLKLEHTDLVPNYALHNAILEWQQL
Length715
PositionTail
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.06
Grand average of hydropathy-0.284
Instability index37.57
Isoelectric point5.45
Molecular weight80798.46
Publications
PubMed=22089132
PubMed=24767513

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01026
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     201.74|      63|     552|      39|     101|       1
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   39-  101 (113.33/79.57)	LHWTTH.KFSGNSIC.LLHIHQPDLVN...SFSKAETNVFEYEPKDHATKAFQEHGSQ....TVHELL.DKYI
  592-  664 (88.41/60.43)	LHQTTQlAYLALRCCeKTWLNRPDLVSeiwSVLKPFRTICIDRRQELTSKKLQRAPSHfvcpIVQEVMeDPYI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     136.72|      45|      46|     226|     271|       3
---------------------------------------------------------------------------
  226-  271 (69.78/65.08)	VHEDDEELQNwRAKEISCR.KEVEVQLAREKQDVQEMKNQRDKIICE
  275-  320 (66.94/54.67)	VQDQSSTLRN.QMLESKCMvTELEEKIISAVDLLISFKEKRDKLRIE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     137.69|      43|     319|     160|     206|       4
---------------------------------------------------------------------------
  160-  206 (67.29/63.97)	PVVLMLDSNTEAkqseKIKSELIPDVLKY.LDSSDMEETENGNSRCSL
  485-  528 (70.40/55.64)	PSKVLLDANFVA....KLGDLGIPSLVQHsMDSADTGTVVCNNSHKHL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01026 with Med32 domain of Kingdom Viridiplantae
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