<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01023

Description Pre-mRNA-processing 40A-like protein
SequenceMDQSKPKAMEREQKKQVRLELLQSQPKISPEYAVGLEGELFVMANNPQQPSSIQFRPVIHAQQGPTFVPMTSQQFGHAGHAVPSSNVGMPAIQGQQLQYSQQMQQLAPRQIQPGHPVSSSQGIPMPYIQTNRPLTSVPQHAQQAVPHINNHMPGLPVSGAPPQSLYTFTPSYGQQQDNANALPQYQHPPQMHAPPAGQPWLSSVPKSAAAVTSVQPSGVQSSGTASTDAATNTTSNNSASDWQEHTAGDGRRYYYNKSTRQSSWEKPLELMSPLERADASTVWKEFTSSEGRKYYYNKVTQQSVWTIPEELKLAREQAHKTISQGMVSETSDTSNAAASSAATSTPPANAASSNTLTPNGLASSPSSVTPVVATDNQRPVSGLSVASVSHSVVTSSTTGVEPSTVVTVSTAPTAVAGSLGVVANSLDSKINSIVENQATHDSTSSVNGTPLQDMEEAKKGVPVVGQTNVTPSEEKTNDGETFVYANKLEAKNAFKALLESVNVHSDWTWEQAMREIINDKRYNALKTLGERKQAFNEYLGQRKKLEAEERRIKQKKAREEFTKMLEECKELTSSTRWSKAISMLENDERFNAVERVRDREDLFESYMVELERKEKENAAEEHRRNLAEYRKFLESCDFVKVNSHWRKIQDRLEDDDRYSLLEKIDRLLVFQDYIRDLEKEEEEQKRIQKERVRRGERKNRDAFRKLLEEHIADGVLTAKTQWRDYCLKVKELPQYQAVASNTSGSTPKDLFEDVFENLEKQYHEDKTLIKDILKSGKITVATTSVFEDFKSAVSEEATCKTISEINLKLLFEELLERAKEKEEKEAKKRQRLADDFTNLLYTLKDIITSSTWEECKALFEDTQEYISIGNESYSKEIFEEYITYLKEKAKEKERKREEEKAKKEKEREEKEKRKEKEKKEKEREREKEKSKERHKKDESDSDNQDMTDGHGYREEKKKEKDKERKHRRRHQSSMDDVDSEKDEKEESRKSRRHGSDRKKSRKHANSPESDNESRHKRHKRDHGDGSRRSGWNEELEDGELGDDAVAEV
Length1048
PositionUnknown
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.06
Grand average of hydropathy-1.073
Instability index54.11
Isoelectric point6.27
Molecular weight119297.92
Publications
PubMed=22089132
PubMed=24767513

Function

Annotated function 
GO - Cellular Component
cytosol	GO:0005829	IEA:EnsemblPlants
mediator complex	GO:0016592	IEA:EnsemblPlants
U1 snRNP	GO:0005685	IBA:GO_Central
U2-type prespliceosome	GO:0071004	IBA:GO_Central

GO - Biological Function
RNA binding	GO:0003723	IBA:GO_Central

GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro
mRNA splicing, via spliceosome	GO:0000398	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01023
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     103.51|      18|      33|      79|      96|       1
---------------------------------------------------------------------------
   46-   63 (25.69/12.59)	NPQQPSSI.QFRPVIHAQQ
   79-   96 (34.87/19.66)	GHAVPSSN.VGMPAIQGQQ
  114-  132 (23.22/10.68)	GHPVSSSQgIPMPYIQTNR
  160-  175 (19.73/ 8.00)	..APPQSL.YTFTPSYGQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      83.05|      25|      26|     886|     910|       2
---------------------------------------------------------------------------
  887-  910 (35.44/14.91)	EKAKE.KERKREEEKAKK.EKE.....REEK.....
  928-  958 (25.26/ 8.54)	EKSKE.RHKKDESDSDNQ.DMTdghgyREEK...kK
  959-  989 (22.35/ 6.72)	EKDKErKHRRRHQSSMDDvDSE.....KDEKeesrK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     461.22|      65|      65|     560|     624|       3
---------------------------------------------------------------------------
  494-  556 (84.50/48.73)	.F..............KALLESV....NVHSDWTWEQAMREIINDKRYNAL...KTLGERKQAFNEYLGQRKK.LEAEE...RRIKQKK
  560-  624 (101.78/60.22)	EF..............TKMLEEC...KELTSSTRWSKAISMLENDERFNAV...ERVRDREDLFESYMVELER.KEKEN...AAEEHRR
  628-  694 (87.73/50.88)	EY..............RKFLESC...DFVKVNSHWRKIQDRLEDDDRYSLL...EKI.DRLLVFQDYIRDLEK.EEEEQkriQKERVRR
  702-  766 (72.71/40.90)	AF..............RKLLEEHiadGVLTAKTQWRDYCLKVKELPQYQAVasnTSGSTPKDLFEDVFENLEK.QYHED.........K
  767-  831 (46.04/23.18)	TLikdilksgkitvatTSVFEDF...KSAVSEEATCKTIS...............EI.NLKLLFEE.L..LERaKEKEE..kEAKKRQR
  835-  927 (68.45/38.07)	DF..............TNLLYTL...KDIITSSTWEECKALFEDTQEYISI...GNESYSKEIFEEYITYLEK.KEKER...EREK...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     137.63|      36|      38|     242|     279|       4
---------------------------------------------------------------------------
  242-  279 (67.53/51.33)	WQEHTAGDGRRYYYNKSTRQSSWEKPLELmsPLERADA
  283-  318 (70.10/46.58)	WKEFTSSEGRKYYYNKVTQQSVWTIPEEL..KLAREQA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     123.87|      29|      35|     363|     391|       5
---------------------------------------------------------------------------
  322-  347 (32.03/16.82)	....ISQGMVSET.......S.............DTSNA..AA.SSAATSTPP
  348-  379 (34.33/18.56)	ANA....AS.SNTltpnglaS.............SPSSV..TP.VVATDNQRP
  380-  412 (35.95/19.78)	VSG.LSVASVSHS....vvtS.............STTGV..EPsTVVTVSTAP
  415-  457 (21.56/ 8.92)	VAGsLGVVANSLD.......SkinsivenqathdSTSSVngTP.L..QDMEEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.52|      20|      35|     139|     159|       6
---------------------------------------------------------------------------
  133-  155 (28.08/26.91)	PLTS..............vpQHAQQAVPHInNHMPGL
  156-  191 (28.44/20.65)	PVSGappqslytftpsygqqQDNANALPQY.QHPPQM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.56|      25|      28|     985|    1012|       7
---------------------------------------------------------------------------
  987- 1012 (40.51/21.84)	SRkSRRHGSDR.KKSRKHA.NSPESDNE
 1013- 1039 (37.05/14.24)	SR.HKRHKRDHgDGSRRSGwNEELEDGE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01023 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) INSIVENQATHDSTSSVNGTPLQDMEEAKKGVPVVGQTNVTPSEEKTNDGETF
2) KERKREEEKAKKEKEREEKEKRKEKEKKEKEREREKEKSKERHKKDESDSDNQDMTDGHGYREEKKKEKDKERKHRRRHQSSMDDVDSEKDEKEESRKSRRHGSDRKKSRKHANSPESDNESRHKRHKRDHGDGSRRSGWNEELEDGELGDDAVAEV
3) SSIQFRPVIHAQQGPTFVPMTSQQFGHAGHAVPSSNVGMPAIQGQQLQYSQQMQQLAPRQIQPGHPVSSSQGIPMPYIQTNRPLTSVPQHAQQAVPHINNHMPGLPVSGAPPQSLYTFTPSYGQQQDNANALPQYQHPPQMHAPPAGQPWLSSVPKSAAAVTSVQPSGVQSSGTASTDAATNTTSNNSASDWQEHTAGDGRRYYYNKST
4) TIPEELKLAREQAHKTISQGMVSETSDTSNAAASSAATSTPPANAASSNTLTPNGLASSPSSVTPVVATDNQRPVSGLSVASVSHSVVTSSTTGVEPSTVVTVSTA
430
892
51
306
482
1048
259
411










Molecular Recognition Features






MoRF SequenceStartStop




1) RHKRHKRDH
2) RRRHQ
3) SGWNEELEDGELGDDAVAEV
1014
967
1029
1022
971
1048