<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01008

Description U-box kinase family protein
SequenceMSTPRSVAVAVSGGSGAAKGSRRALQWAMENVVPQADRLILVHVIPKITSIPTPAGGYIPISEADAHAFAAYVQDVKQKSEEIFVSFKKLCESNTIETFLLEDDNPANALLSFISESGVQILVLGSDDSNFITRKLKGPGIPTTILRCAPDSCDVYVVDRDRIVSKLADSLSSHSHEEGPRYTVSNQINKSDNGAGVGGQMSGISASSTELKVLKNFRFLSISEHSYIGLQTSSRRSSFENSTISEEANPENYGDYVDTISLRSFDSIASAYHEPLVMQEVERLQLELQNTISMYKQVCEELVHAQSKALLLSSESLEEAKIINASLKREETLRKIAAEEKAKYLKVMKELEESKSMFAKESYERQMAELNVLRESIEKQRIVDTLLSNDRRYRKYTMDEIKIATNNLSGDLVIGEGGYGKVYKCNLDHTPVAVKVLHQDTINKKAEFLKEVEILSQLHHPNMVLLLGACPENGCLVYEYLENGSLEDYLLNRNEKPPLPWFFRFRIIFEMACGLSFLHNSKPEPIVHRDIKPGNVLLDRNYVSKISDVGLAKLISDVVPDNITEYRESVLAGTLHYMDPEYQRTGTVRPKSDVYAFGVIILQLITARHARGLITTIEDAITNGSFRDILDKSAGDWPLNETIELAEIGLKCTSLRCRDRPELDTEVLPLLKRLSDMANASVKIGRSSAHTPSQYYCPILQEIMDEPYIAADGFTYEHRAIKAWLSKHNVSPVTKHKLQHSELTPNHTLRSAIQEWKSEVTLLD
Length764
PositionTail
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.07
Grand average of hydropathy-0.296
Instability index43.28
Isoelectric point5.75
Molecular weight85487.27
Publications
PubMed=22089132
PubMed=24767513
PubMed=30397259

Function

Annotated function Functions as an E3 ubiquitin ligase.
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP01008
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     169.71|      53|     135|     466|     524|       1
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  466-  524 (90.96/76.33)	LLGACPENGCL..VYEYLENGSLEDYLlnrnEKPPLPWFFRFRIifEMA.CGL...SFLHNSKPE
  604-  662 (78.76/51.19)	LITARHARGLIttIEDAITNGSFRDIL....DKSAGDWPLNETI..ELAeIGLkctSLRCRDRPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.95|      35|      47|     306|     352|       2
---------------------------------------------------------------------------
  306-  340 (52.10/44.44)	QSKALLLSS.............ESLEEAKIINASLKREETLRKIAAEE
  353-  400 (48.85/21.65)	ESKSMFAKEsyerqmaelnvlrESIEKQRIVDTLLSNDRRYRKYTMDE
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.35|      37|      55|     129|     165|       3
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  129-  165 (64.71/42.21)	SNFITRKLKGPGIPTTILRCAPDSCDVYVVDRDRIVS
  185-  221 (60.63/39.12)	SNQINKSDNGAGVGGQMSGISASSTELKVLKNFRFLS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.40|      31|     637|      31|      61|       4
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   31-   61 (55.90/35.56)	NVVPQADRLI.LVHVIPKI..TSIPTPAGGYIPI
  666-  699 (46.49/28.43)	EVLPLLKRLSdMANASVKIgrSSAHTPSQYYCPI
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Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP01008 with Med32 domain of Kingdom Viridiplantae

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