<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01006

Description Mediator complex subunit 25 von willebrand factor type A protein
SequenceMENKRWLNIVVDGNKALEKYWTDILSNYLEKIVRCFVGESQEQESYLGLVLYNANSELVEAGYDMQFINWTKDVNKFMENLSHLSFNGNDANQSTMAEGLAEALVMYPKPCDTMTEREYYISERHCILVAPGDPAPKSMLVCLPMIQRAQVIGQRLKACQADFLEVAKTCIPLSVSLSVITPNPVPIFGAIFNMGNNALTLSNAPISSYSTGQLTVLLSKNFREAHVALKEKGIMEYPSTTSVGSISAAPDTTLFRAFSTNLQEEQVSSSMAIGDTIRETDNTITPEPVSTSQHNSQENIVQMNLYEDIMSELDDDDLFTPNKRSKTFAPLEDDPDLQDFFKFDQNPFEGFDQFIKQDQQVFNQQEIPTEEAVFNQQQIPTEEAGVDFANELQEILNGASRNTSTAQTANVECTTSSFQEVNKYVAPASNVGEGSSTGLLHESNLQSWYNPHAMTSTSKLDSQSFPTNAFNGNMTSTSTLDSRSFSTNNFNGNFTLSNVMGNSQMQQLQPGSSQNQFSMSPGFARGQVGNFSVQPMGQHFQACNQFLRNNNTASYNLPAFGANTWLRPMPSLSPSYPSASMCFPTLKEIQDYVQTWEGTLAGKITSSRITILRAKAFRKSSTPPTLTLDWPGRLEISNYLPQKALLHTRRFSQPIHYLFFHVAKYSNVDLYNHCKTRNNCAKVDLQFQTIILSPTEREPLFVGTVFPGVSIIF
Length713
PositionUnknown
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.10
Grand average of hydropathy-0.372
Instability index45.20
Isoelectric point4.98
Molecular weight79612.36
Publications
PubMed=22089132
PubMed=24767513

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
transcription regulator complex	GO:0005667	IBA:GO_Central

GO - Biological Function
GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01006
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.59|      17|      17|     457|     473|       1
---------------------------------------------------------------------------
  457-  473 (34.21/19.43)	TSKLDSQSFPTNAFNGN
  477-  493 (34.38/19.56)	TSTLDSRSFSTNNFNGN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.99|      15|      17|     544|     558|       2
---------------------------------------------------------------------------
  544-  558 (27.41/15.37)	NQFLRNNNTASYNLP
  563-  577 (30.58/17.99)	NTWLRPMPSLSPSYP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.03|      15|      19|     256|     270|       3
---------------------------------------------------------------------------
  256-  270 (24.27/11.95)	RAFSTNLQEEQVSSS
  278-  292 (25.77/13.06)	RETDNTITPEPVSTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.01|      15|      19|     402|     420|       4
---------------------------------------------------------------------------
  402-  416 (25.43/23.21)	NTSTAQTANVECTTS
  422-  436 (25.58/10.96)	NKYVAPASNVGEGSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.32|      27|     381|     131|     159|       6
---------------------------------------------------------------------------
  131-  159 (45.90/38.18)	PGDPAPKSMLVclPMIQRAQV.......IGQRLKAC
  510-  543 (46.42/30.77)	PGSSQNQFSMS..PGFARGQVgnfsvqpMGQHFQAC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01006 with Med25 domain of Kingdom Viridiplantae
Unable to open file!