<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01003

Description Mediator of RNA polymerase II transcription subunit 36a
SequenceMAPPRGRGGFGGRGGGRGARGGGRGRGGGRGGMKGGSKVVVEPHRHEGIFIAKGKEDALVTKNLVPGEAVYNEKRVSVQNEDGTKVEYRIWNPFRSKLAAAVLGGVDNIWIKPGAKVLYLGAASGTTVSHVSDIVGPTGVVYAVEFSHRSGRDLVNMAKKRTNVIPIIEDARHPAKYRMLVGMVDVIFSDVAQPDQARILGLNASYYLKAGGHFVISIKANCIDSTVPAEAVFSSEVNKLKADQFKPFEQVTLEPFERDHACVVGGYRMPKKKKDAE
Length277
PositionUnknown
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.07
Grand average of hydropathy-0.301
Instability index28.17
Isoelectric point9.77
Molecular weight29739.76
Publications
PubMed=22089132
PubMed=24767513
PubMed=30397259

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
methyltransferase activity	GO:0008168	IEA:UniProtKB-KW
RNA binding	GO:0003723	IEA:UniProtKB-KW

GO - Biological Process
methylation	GO:0032259	IEA:UniProtKB-KW
rRNA processing	GO:0006364	IEA:UniProtKB-KW









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01003
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.31|      12|      16|       5|      18|       1
---------------------------------------------------------------------------
    5-   18 (22.74/12.83)	RGRGgfGGRGGGRG
   24-   35 (27.57/10.15)	RGRG..GGRGGMKG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.03|      17|      17|     158|     174|       2
---------------------------------------------------------------------------
  138-  161 (20.30/11.20)	TGVVYAVEfshrsgrDLVNMAKKR
  162-  178 (30.72/20.02)	TNVIPIIE.......DARHPAKYR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     162.25|      53|     159|      48|     105|       4
---------------------------------------------------------------------------
   48-  105 (74.44/59.64)	GIFIAKGKEDALvtKNLVPGEAVYNEKRVSVQNEDGTKVEYRiwNPFRSKlAAAVLGG
  212-  266 (87.81/59.23)	GHFVISIKANCI..DSTVPAEAVFSSEVNKLKADQFKPFEQVtlEPFERD.HACVVGG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01003 with Med36 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MAPPRGRGGFGGRGGGRGARGGGRGRGGGRGGMKGGSKV
1
39










Molecular Recognition Features






MoRF SequenceStartStop




1) MAPPRGRGGF
1
10