<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00992

Description Mediator of RNA polymerase II transcription subunit 36a
SequenceMAPPRGRGGFGGRGGDRGGRGGGGGRGFGGGRGGDFKPRGGGRGFGGGRGARGGGRGRGGGRGGMKGGSKVVVEPHRHEGIFIAKGKEDALVTKNLVPGEAVYNEKRVSVQNEDGTKVEYRIWNPFRSKLAAAVLGGVDNIWIKPGAKVLYLGAASGTTVSHVSDIVGPTGVVYAVEFSHRSGRDLVNMAKKRTNVIPIIEDARHPAKYRMLVGMVDVIFSDVAQPDQARILGLNASYYLKAGGHFVISIKANCIDSTVPAEAVFSSEVNKLKADQFKPFEQVTLEPFERDHACVVGGYRMPKKKKDAE
Length309
PositionUnknown
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.07
Grand average of hydropathy-0.395
Instability index27.57
Isoelectric point10.02
Molecular weight32657.83
Publications
PubMed=22089132
PubMed=24767513

Function

Annotated function 
GO - Cellular Component
box C/D RNP complex	GO:0031428	IBA:GO_Central
Cajal body	GO:0015030	IBA:GO_Central
small-subunit processome	GO:0032040	IBA:GO_Central

GO - Biological Function
histone-glutamine methyltransferase activity	GO:1990259	IBA:GO_Central
RNA binding	GO:0003723	IBA:GO_Central
rRNA methyltransferase activity	GO:0008649	IBA:GO_Central

GO - Biological Process
box C/D RNA 3'-end processing	GO:0000494	IBA:GO_Central
histone glutamine methylation	GO:1990258	IBA:GO_Central
rRNA methylation	GO:0031167	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00992
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      94.85|      15|      16|      20|      34|       1
---------------------------------------------------------------------------
    6-   24 (29.85/ 7.73)	GRGGFGGRGGdrggRGGGG
   25-   41 (30.25/ 7.92)	GRGFGGGRGG..dfKPRGG
   42-   56 (34.76/10.11)	GRGFGGGRGA....RGGGR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.03|      17|      17|     190|     206|       2
---------------------------------------------------------------------------
  170-  193 (20.30/11.92)	TGVVYAVEfshrsgrDLVNMAKKR
  194-  210 (30.72/21.26)	TNVIPIIE.......DARHPAKYR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00992 with Med36 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MAPPRGRGGFGGRGGDRGGRGGGGGRGFGGGRGGDFKPRGGGRGFGGGRGARGGGRGRGGGRGGMKGGSKV
1
71










Molecular Recognition Features






MoRF SequenceStartStop




1) GGGGGRGFGGGRGGDFKPRGGGRGFGGG
2) MAPPRGRGGFGGRGGDRGG
21
1
48
19