<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00988

Description Mediator of RNA polymerase II transcription subunit 33A
SequenceMENAMDSRQIPIKSAIEVLTEGIKTLQIFNQASWHETFLALWLSALRLVQRERDPPEGPIPHLEARLCMLLSIVPLVIVNVLRDDTEHNLSTAPVSVGSEYKHEMKSDLSMKLGLISSVQVLGHFSGLLCPPALVVDAANQAARKASSFIYNSMKEKGEPFTSINANANSNAGGNLRHLIVEACIARNLMDTSVYFWPGYVSTSVMSLSDSTPLGKSPWLTFMEGTPLNNSLINALAATPASSIAEIEKLYYIALSGSEVERPTAAKILCGASLSRGWYIQEHVVHYVVKLLACPVPHSNSGTRGLFVDNMSMISAVLRGASSVDTLHILSLHGVVPTVAASLLPLCEAFGSISPTPISTGDESSTSVYMAFSLAFLFLIRLWKFCRPPLDQCITEGGIAVGGLEYLLSLHNNCVMSSQDKQKSNQNLFDSASFKPVYIDSFPKLRALYCQYKSCVASTLSGISTGNSIHQTASVILSMIYQKMSKGGISSSNSSSPNSSNACSALINSGEDALQRPVLPAWEVLEALPFVLEAILTACVHGRLSSRDLTTGLRDLVDFLPASIAAIIDYFSSEVTRGVWKQVPMNGTDWPSPAAVLQSVESEIKAILTHVGVEVPNCSSGGSPVTLPLPMAALVSLSITFKLDKSLEYIHAITGAALENCASGCPWPSMPVIGSLWAQKVRRWHNFIVVSGSRSVFRHNNESVAQLVRSCFTSFLGVLSGSNSKLTAECSVNGLLGSSITAPGAFPFVAPGFLYLRSCRDIHNVQYLNDVIVGLVTEYSNELAGIRASSGSSRLKSNESSLFLAAQSAKEMATLGASLLCSAGGIQLVQELYKETIPTWLLSSRDVKRKNDNVMSYILEGYAIAYLLTFSGSILWGVGTKLPSPKLSRRNHTIGVHLDFLAEVMERKISLSCNPITWKTYVCCLVGLMVSFAPAWLQEMKVDSLRKLAHGLSRWNEHELALSLLQRGGTAAMGALAELINVIEFEHKKPCS
Length992
PositionTail
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.07
Grand average of hydropathy0.184
Instability index47.27
Isoelectric point7.08
Molecular weight107293.54
Publications
PubMed=22089132
PubMed=24767513

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00988
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     512.93|     166|     296|     405|     584|       3
---------------------------------------------------------------------------
  405-  584 (259.48/170.65)	EYLLSLHNNCVMS.......SQDK...QKSNQNLFDSASFKPvyiDSFPKLRALYCQYKSCvastlSGIstgNSIHQTASVILSMIYQ.KMSKGGISSSNSSSPNSSNAcSALINSGEDALQRPVLPAWEVLEA..LPFVLEAILTACVHGRLSSRDLTTGLRDLVDFLPASIAaiIDY...FSSEVTRGVWKQVP
  702-  883 (253.45/137.86)	ESVAQLVRSCFTSflgvlsgSNSKltaECSVNGLLGSSITAP...GAFPFVAPGFLYLRSC.....RDI...HNVQYLNDVIVGLVTEySNELAGIRASSGSSRLKSNE.SSLFLAAQSAKEMATLGASLLCSAggIQLVQELYKETIPTWLLSSRDVKRKNDNVMSYILEGYA..IAYlltFSGSILWGVGTKLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.33|      28|     176|      42|     104|       4
---------------------------------------------------------------------------
   73-  100 (46.68/59.96)	IVPLVIVNVLR.DDTEHNLSTAPVSVGSE
  335-  363 (44.65/ 6.82)	VVPTVAASLLPlCEAFGSISPTPISTGDE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     127.39|      38|     648|     253|     291|       5
---------------------------------------------------------------------------
  253-  291 (61.47/40.28)	IALSGSEVERPTAAKILCG..ASLSRGWyIQEHVVHYVVKL
  909-  948 (65.92/38.52)	ISLSCNPITWKTYVCCLVGlmVSFAPAW.LQEMKVDSLRKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.62|      13|     648|      34|      54|       6
---------------------------------------------------------------------------
   34-   51 (19.57/27.06)	WHETFLalwlsALRLVQR
  955-  967 (25.05/ 9.27)	WNEHEL.....ALSLLQR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00988 with Med33 domain of Kingdom Viridiplantae
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