<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP00980

Description Heat shock cognate 70 kDa-like protein
SequenceMARSSSCGSVLLLTIISLVCLFATSAAKEEGTTKLGTVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVSFTDDERLIGEAAKNLAAVNPERTIFDVKRLIGRKFADKEVQRDMKLVPYKIVNKDGKPYIQVRVKDGETKVFSPEEVSAMILTKMKETAEAFLGKTIRDAVVTVPAYFNDAQRQATKDAGVIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSILTIDNGVFEVLSTNGDTHLGGEDFDQRIMEYFIKLIKKKHSKDISKDNRALGKLRRESERAKRALSSQHQVRVEIESLFDGVDFSEPLTRARFEELNNDLFRKTMGPVKKAMDDAGLQKNQIDEIVLVGGSTRIPKVQQLLKDYFDGKEPNKGVNPDEAVAFGAAVQGSILSGEGGVETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVSIQVFEGERSLTKDCRLLGNFDLSGIPPAPRGTPQIEVTFEVDANGILNVRAEDKGTGKSEKITITNEKGRLSQEEIDRMVREAEEFAEEDKKVKERIDARNALETYVYNMKNQISDKDKLADKLESDEKEKIEAAVKEALEWLDDNQTVEKEEFEEKLKEVEAVCNPIITAVYQRSGGAPGGASGEGEDEDEDSRDEL
Length669
PositionUnknown
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.06
Grand average of hydropathy-0.418
Instability index29.59
Isoelectric point5.02
Molecular weight73642.48
Publications
PubMed=22089132
PubMed=24767513

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
endoplasmic reticulum chaperone complex	GO:0034663	IBA:GO_Central
endoplasmic reticulum lumen	GO:0005788	IBA:GO_Central
membrane	GO:0016020	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
endoplasmic reticulum unfolded protein response	GO:0030968	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central
ubiquitin-dependent ERAD pathway	GO:0030433	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP00980
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.92|      15|      20|     416|     430|       2
---------------------------------------------------------------------------
  416-  430 (26.48/15.70)	GGVETKDILLLDVAP
  439-  453 (28.44/17.33)	GGVMTKLIPRNTVIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.30|      11|      27|     232|     242|       6
---------------------------------------------------------------------------
  232-  242 (20.46/12.81)	LGGGTFDVSIL
  260-  270 (21.85/14.22)	LGGEDFDQRIM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.65|      13|      19|     101|     114|       7
---------------------------------------------------------------------------
  101-  114 (17.44/16.00)	DVKrLIGRKFADKE
  118-  130 (23.21/15.49)	DMK.LVPYKIVNKD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.72|      11|      20|     538|     548|       8
---------------------------------------------------------------------------
  538-  548 (18.03/10.24)	EKGRLSQEEID
  559-  569 (17.69/ 9.91)	EEDKKVKERID
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.87|      16|      21|     492|     507|      10
---------------------------------------------------------------------------
  492-  507 (30.37/20.42)	DLSGI...PPAPRGTPQIE
  513-  531 (22.49/13.06)	DANGIlnvRAEDKGTGKSE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP00980 with Med37 domain of Kingdom Viridiplantae
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